2008年Cell杂志的一期不错的干细胞特刊

yusheen

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最近浏览期刊，发现2008年Cell杂志有一期干细胞研究的综述，内容非常全面，感觉对大家非常有用，可以作为教材来研究学习。下载时把文章的补充材料也下下来，供大家学习。- f' @) V3 _- R# d3 |
Stem cells have two remarkable abilities: they can self-renew to keep the stem cell pool replenished, and! U) ^/ S! \) F  W
they can differentiate into a wide variety of cell types. This stunning biological duality intrigues not only5 |' @  _( Z9 S  C1 _! A( S
those interested in the basic mechanisms of development, differentiation, and reprogramming, but
* F4 B/ @. k0 ?also those who seek to use stem cells therapeutically to replace lost or damaged tissue. But when did
" V9 N0 R' l) w2 A/ `- V3 m$ C3 Uthe stem cell revolution start? It was back in the 1960s that two Canadian researchers, Ernest A. McCulloch
' B7 ]. A3 q' _. _1 }) `1 M& uand James E. Till, launched the field of stem cell research with their groundbreaking work on the hematopoietic
: P( G1 q% C2 `2 Mstem cells of mouse bone marrow. By designing clonogenic assays to measure stem cell differentiation
$ a) {9 m6 q  v. jin vitro and serial transplantation assays to study stem cell repopulating ability in vivo, Till and! P; k, R0 r4 L- j& L& Z" R
McCulloch defined the hallmark characteristics of stem cells.$ i1 O% K. \6 _  ~9 D6 y
The field of stem cell research has come a long way in 50 years, as we hope will be apparent from this/ Z4 D7 Z+ j8 C6 U+ D- P
year’s Special Review Issue. Our goal in this issue is to highlight the remarkable biological features of
6 i8 o& Q9 c* s0 s8 O9 N  ?stem cells, the molecular pathways that control these characteristics, and the ways in which these enigmatic
( p! a$ v- O% {8 o( F5 c5 fcells can be exploited for cell replacement therapy. We would like to thank the many distinguished
1 I  W1 N1 \& |7 A; @7 x& I% z3 V+ [) Nexperts who contributed their time and efforts as authors and reviewers to make this special issue on
: F7 Z* R/ R* O2 zstem cells informative, thought-provoking, and timely. We hope that this collection of articles conveys
# O4 B6 p: P0 I3 S4 ]- Ethe excitement and promise of stem cell research, as we enter a new era of possibility.

yusheen

回复 yusheen 的帖子4 E9 x  k. ^/ i( Z4 y9 D" o6 s: x+ t
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顶一个

chuanbaozang

赞一个

exin11

看看

flydayzhu

look 一下

linlicau

辛苦了，要点包包也能理解。

ayeqiu

下载看看~

ayeqiu

为啥每次都提示“你所在的用户组无法下载或查看附件”…………晕！晕！！晕！！！……

tpwang

回复 ayeqiu 的帖子# W, S6 p  i: U4 Q

2 C+ ?2 M. i; D+ }你的积分还差9分就可以成为注册会员了，加油。
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参加一些讨论是增加积分的最好办法。

ayeqiu

回复 tpwang 的帖子0 o3 U3 w  R5 Y) y' j" [" o

5 B% t0 T9 n6 B原来是这样啊，谢谢你！