2008年Cell杂志的一期不错的干细胞特刊

yusheen

0 ~* w, h$ s" V4 X2 q* U& a/ ^, M

  N' L0 U+ c4 G. g% d% b% g! p) i最近浏览期刊，发现2008年Cell杂志有一期干细胞研究的综述，内容非常全面，感觉对大家非常有用，可以作为教材来研究学习。下载时把文章的补充材料也下下来，供大家学习。8 W' {" U9 R5 {; `7 [2 s7 v
Stem cells have two remarkable abilities: they can self-renew to keep the stem cell pool replenished, and
2 y6 Z6 u3 u  x5 zthey can differentiate into a wide variety of cell types. This stunning biological duality intrigues not only
( T; U2 Z: A) n$ _: d$ d; ythose interested in the basic mechanisms of development, differentiation, and reprogramming, but$ G" M# a8 C5 t& t! b8 e
also those who seek to use stem cells therapeutically to replace lost or damaged tissue. But when did, H- L, F: t# _+ `9 k, n
the stem cell revolution start? It was back in the 1960s that two Canadian researchers, Ernest A. McCulloch
# j2 R+ j" ]* @& }and James E. Till, launched the field of stem cell research with their groundbreaking work on the hematopoietic
. {2 U, z( |7 W9 N6 i6 astem cells of mouse bone marrow. By designing clonogenic assays to measure stem cell differentiation; e+ M4 ?$ i& @1 r1 \" i# T
in vitro and serial transplantation assays to study stem cell repopulating ability in vivo, Till and0 [& p; u( _% j) j
McCulloch defined the hallmark characteristics of stem cells.4 H" V. n; j- A% K
The field of stem cell research has come a long way in 50 years, as we hope will be apparent from this1 V0 z/ v4 ^/ F
year’s Special Review Issue. Our goal in this issue is to highlight the remarkable biological features of
# l+ ]* e# }* Rstem cells, the molecular pathways that control these characteristics, and the ways in which these enigmatic
: u% ^' G& A* u7 X8 n4 u( pcells can be exploited for cell replacement therapy. We would like to thank the many distinguished5 r. @5 G2 C2 e
experts who contributed their time and efforts as authors and reviewers to make this special issue on
( U# j' L1 |1 e* b7 o% b3 Kstem cells informative, thought-provoking, and timely. We hope that this collection of articles conveys
, E% M* H$ S$ b9 |$ I+ Uthe excitement and promise of stem cell research, as we enter a new era of possibility.

yusheen

回复 yusheen 的帖子5 X: K  R2 Z# b: K2 |* Z; K

  l: r) f. {3 O  s顶一个

chuanbaozang

赞一个

exin11

看看

flydayzhu

look 一下

linlicau

辛苦了，要点包包也能理解。

ayeqiu

下载看看~

ayeqiu

为啥每次都提示“你所在的用户组无法下载或查看附件”…………晕！晕！！晕！！！……

tpwang

回复 ayeqiu 的帖子
2 p7 l; G2 v& z; \: L( F
8 M* q* e! u, [3 `你的积分还差9分就可以成为注册会员了，加油。1 b0 p" P6 {0 x, P2 ]

. w) e. H/ G  i- O9 G参加一些讨论是增加积分的最好办法。

ayeqiu

回复 tpwang 的帖子
! x# c# A$ X' z8 P. x4 ^/ H; }3 s
原来是这样啊，谢谢你！