Review stem cell

bridgeyangfan

Emerging models and paradigms for stem cell ageing - ?( w/ Q$ e4 `  r+ s! J2 X' g) `8 |
D. Leanne Jones and Thomas A. Rando
8 t$ q( Y, z; Q6 {$ j; h, y6 aAgeing is accompanied by a progressive decline in stem cell function, resulting in less effective tissue homeostasis and repair.2 j, ]8 Y9 u) Y, R3 m2 [
Here we discuss emerging invertebrate models that provide insights into molecular pathways of age-related stem cell dysfunction( p) E$ m( W/ \) j4 z& ^
in mammals, and we present various paradigms of how stem cell functionality changes with age, including impaired self-renewal2 A5 V: ?1 h; K$ z
and aberrant differentiation potential.6 o( D: P9 T( T, W" I# S, f
"Nature cell biology 13(5) 2011"$ \/ z; {& r5 D# x( W

liuer0041

了解一下，谢谢

wandersnow

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唐超

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hxw123

Thanks!

cheese

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