1998-nature-Dendritic cells and the control of immunity

andylee824

   B and T lymphocytes are the mediators of immunity, but their function is under the control of dendritic cells. Dendritic1 `1 f! L/ e+ v' `
cells in the periphery capture and process antigens, express lymphocyte co-stimulatory molecules, migrate to
  X& k/ u0 d2 `8 _1 D" Ylymphoid organs and secrete cytokines to initiate immune responses. They not only activate lymphocytes, they also
2 b* n  n5 b( B5 e0 w( b  mtolerize Tcells to antigens that are innate to the body (self-antigens), thereby minimizing autoimmune reactions. Once
! Y& v3 h7 j! D: g" ra neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell6 [3 p) T; ?5 _
biological analysis. With knowledge comes the realization that these cells are a powerful tool for manipulating the
) w* K* V6 L' U, ^' ]; I( x3 nimmune system.

andylee824

自己顶一下！

andylee824

自己顶一下！