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Non-Viral Gene Therapy. J$ u7 X9 L$ @
Edited by: Xu-bo Yuan
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ISBN 978-953-307-538-9, Hard cover, 696 pages$ F' h" m* @5 d
Publisher: InTech2 W1 z! t. ~# k% v% ^
Publication date: November 2011
) n; b$ J/ ?1 x' c% W9 R4 USubject: Gene Therapy* o7 {' B3 t- d$ m5 u+ O
: _( A3 G: r, j, J8 ~4 o+ ]This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation./ c) ?( G1 [3 U8 _( K
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Table of Contents+ } Q& a l9 l9 ~: c
Non-Viral Gene Therapy Vectors Carrying Genomic Constructs
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8 M! }+ b% v1 W# [Non-Viral Delivery Systems in Gene Therapy and Vaccine Development2 T$ Y% ^% e% N# f) h7 x i7 t
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Gene Delivery Systems: Tailoring Vectors to Reach Specific Tissues5 G- k8 {1 O7 ]. B
& I1 y5 V1 H4 P! ~/ PInvestigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines
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The Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy. @( f& U8 u# `# g
; Y( F4 i8 _1 [) w2 ^, Y" j! s* G q$ ]Gene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients# _8 |8 m0 t% p( o# i) y8 N7 h
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Non Viral Gene Transfer Approaches for Lysosomal Storage Disorders
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DNA Vaccination by Electrogene Transfer. Z: e0 p4 p: R" m7 B V+ y X
* h! j1 o" q+ _, kGene Delivery with Ultrasound and Microbubbles
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Ultrasound-Mediated Gene Delivery
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( j" C9 e2 N5 I- o6 _ ]Polyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity
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Technological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy
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6 o* W0 ^( {2 O' v8 W. }Cationic Liposomes in Different Structural Levels for Gene Delivery+ o+ d/ |! @/ d
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Neutral Liposomes and DNA Transfection
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& ~' Q& F1 Q' ~! ^Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships
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Polycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process
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$ b7 v. f; N# b# l3 ]Medical Polymer-Based Gene Therapy
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Chitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?
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Chitosan-DNA/siRNA Nanoparticles for Gene Therapy1 o- ]; R3 R' l8 j8 C2 J4 y$ T; i+ A: o
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Toxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application7 g- n7 p. L& v
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PAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy
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; e# A7 I/ d# U. n2 kNanomedicine Based Approaches to Cancer Diagonsis and Therapy
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& O8 G6 y; @1 w' \+ uToxicogenomics of Nonviral Cationic Gene Delivery Nanosystems7 H( I+ X: K* O
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Nano-Particulate Calcium Phosphate as a Gene Delivery System
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Modular Multifunctional Protein Vectors for Gene Therapy
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Peptides as Promising Non-Viral Vectors for Gene Therapy
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Binding of Protein-Functionalized Entities onto Synthetic Vesicles! l$ r1 E/ a5 j+ h4 q5 D( Y# r$ j
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Targeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells
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. h# T$ X( p4 Y) ~* XPyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics4 q# {( Q Z' k X7 h: j
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