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从权威杂志 blood, cancer research, cancer cell, cell ,cell stem cell, cell research, stem cells, PNAS, nature 系列等收集了74篇研究性论文,与大家分享。
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/ v; e6 @& [" E2 V) A: p" A0 \Jiang, X. 2010 Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
+ o' y, L! @& ?% \. ]; y+ SBlood- O0 J! p% D( U" Y
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Peng, C. 2010 PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
/ J& ~* M) e0 x S _' G$ b% \Blood
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Sengupta, A. 2010 Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.3 m* a6 e8 {+ C9 u! j
Blood( v9 P8 N6 g5 f% s. j. _
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" U* r/ P3 m4 CSmith, A. C. 2010 High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
. i: ~9 S" u% C# G+ L' O' d! r. l6 \Blood
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Taussig, D. C. 2010 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.) H3 }+ a# N& [* _" F
Blood& A* A, b, V7 T3 @2 h: C R( Z
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Chen, R. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
' E' f/ |% ?: \) z/ |, D9 eCancer Cell) y! a- N# p5 Z& J' w& Y9 j
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Yeung, J. 2010 β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.
. e6 l5 o3 s) Z0 Q! _Cancer Cell+ U, Y- O& i5 T L& J
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Zhang, B. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
% L, }- k( M& j9 b, f$ |1 C, q0 ?% DCancer Cell
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Biernacki, M. A. 2010 Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.6 ^% M+ t# h: F0 h1 S5 _
Cancer Res& {1 u M( X( A4 Q! J5 S% ^
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Bonnefoix, T. 2010 Cancer stem cells promote tumor vascular development--letter.
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5 r: X2 n4 z. Z/ QCammareri, P. 2010 Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.
# g- }/ I+ t) w* B7 z0 S% \Cancer Res
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/ t( ?/ a+ }1 d* D& K. e0 KChiou, S. H. 2010 Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.
. V4 N- u0 ~# ?) R6 Z, a/ j0 p0 R1 SCancer Res4 ~, c- ~% I8 J, t0 i
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Deka, J. 2010 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.
/ j7 e& K8 B$ L+ wCancer Res
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Harrison, H. 2010 Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.1 ~, \0 ^4 `% k% i% H9 u7 ]
Cancer Res
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7 j4 a* w2 Y5 KHebbard, L. W. 2010 Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo., }& Y+ b" \: c5 y1 ?
Cancer Res
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Held, M. A. 2010 Characterization of melanoma cells capable of propagating tumors from a single cell.. c7 E& D! w5 |' X0 {0 K% U
Cancer Res0 ]$ b+ c4 Y1 e
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Jin, Y. 2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
. E# E6 P( t: UCancer Res" X' q* i! e$ ^$ q' y
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Jo, M. 2010 Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
2 W- c+ a" n* D5 UCancer Res7 P9 V0 K: w |5 v
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Joseph, I. 2010 The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.
6 L9 Y; O! `( f" F+ _) hCancer Res9 S+ k% b3 N% Z# i+ _/ B$ E
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7 ~0 s( O+ n) `! j% TKemper, K. 2010 The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.& M5 l' a5 C" }' ?$ B D2 i
Cancer Res
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+ n2 A, ~3 }; D |6 \Krishnamurthy, S. 2010 Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.
( s5 y) B( F% SCancer Res
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8 W; G) W m/ M7 z+ x/ R' v8 p+ `Lee, J. H. 2010 Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.
" ?* S. V& q" _9 m% f& mCancer Res
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Levina, V. 2010 Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.' r; x/ F- v3 h! q
Cancer Res+ Q( g2 Q: c' p) F8 u) \, X/ d
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Liao, C. P. 2010 Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells.7 R! l1 O! }/ P" ]0 a7 O
Cancer Res
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/ g8 B' f/ n- n1 i/ kLiu, M. 2010 The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.8 b" X7 l, c# O" F4 W, R
Cancer Res6 @; i2 h; m5 I- b
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Lottaz, C. 2010 Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.7 R/ k* J) P, ]# {3 A
Cancer Res
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% K! A# J8 x2 m6 fMazzoleni, S. 2010 Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.
: q. T% r8 u, I* s( LCancer Res2 }5 b4 p$ I8 B, c# i
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Ooi, A. T. 2010 Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
2 l8 w; k& |( t, v$ J9 M9 |4 c% OCancer Res
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- t8 ?5 ^7 h" _% o9 FReiman, J. M. 2010 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.; Y* F9 f8 }- {
Cancer Res. S" q" U5 n- j3 S& H2 M" f
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Schatton, T. 2010 Modulation of T-cell activation by malignant melanoma initiating cells.- Q8 a, I& x$ d) P$ Q3 L# }
Cancer Res& s) j* _0 I' @4 \7 ^6 U- z" s
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Sikandar, S. S. 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.) O4 @2 w# V# M! ^
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H- s! \, z$ s8 v, `: WSottoriva, A. 2010 Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.5 E/ R0 A' y1 H
Cancer Res
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|) Y5 _, D# V' ]6 I4 W7 ?3 l. J0 ~Sullivan, J. P. 2010 Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
0 n2 ]* M, Q- o9 t$ ^Cancer Res
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' X) ^( P6 I) {. t5 BTodaro, M. 2010 Tumorigenic and metastatic activity of human thyroid cancer stem cells.
4 u' _8 v) d' i! B7 h$ c! _Cancer Res3 ?0 C9 g) ^7 A P% J5 [
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7 K! r! C) z9 `- T8 H+ J; C7 a! MWong, P. 2010 The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. ]0 \0 j" d! B: i- N4 s: ?
Cancer Res
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Yang, X. 2010 Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.( Z7 \% H5 O J, [5 d
Cancer Res$ d) t1 c# `, F; Y1 @1 D
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( n. ]8 ]$ L- R$ \" r2 ]6 C: ^7 KPece, S. 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.% D( j" e( O- @9 ?& V
Cell4 t* _% j' }* {9 ]2 V" F+ \. m4 Q
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Roesch, A. 2010 A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.0 ~( @2 e/ p' a2 i1 x
Cell8 y# W: n, ~$ J& N( ]7 C( `
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Charles, N. 2010 Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.8 S% {6 o B7 B$ W+ x4 o! x
Cell Stem Cell/ L* L4 W: N0 ]$ D3 \" i
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( {: u& l7 Y# m' wKikushige, Y. 2010 TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.
; ]6 {0 ^! E$ VCell Stem Cell1 R4 f, {; a/ z
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8 W5 l9 W; Y' E1 T1 jLathia, J. D. 2010 Integrin alpha 6 regulates glioblastoma stem cells.
8 V; r% m. Y; x5 g$ xCell Stem Cell
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Ma, S. 2010 miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.- d1 y5 P- V0 t: p5 x
Cell Stem Cell
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# R2 s% M7 F" v# N/ e, J7 M. OPang, R. 2010 A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.( R- ~4 k. g# i1 p" ~$ h# r2 E* o0 q! \
Cell Stem Cell) x; Q, Y9 W5 ^0 D: W
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% p1 e3 T( c/ i% L: m! l/ oWurdak, H. 2010 An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.% m" p( ?* X9 D K- ?
Cell Stem Cell
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Yang, X. R. 2010 High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.
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You, H. 2010 Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.
, {# q) M9 |" t4 W5 qHepatology6 i! x2 R, g# D* g s% _
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5 {1 r' e, I; iCalcagno, A. M. 2010 Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics.
. l3 J- F& b8 r1 C. zJ Natl Cancer Inst
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Tehranchi, R. 2010 Persistent malignant stem cells in del(5q) myelodysplasia in remission.
: |) a& S; {# P7 pN Engl J Med# _- p) {; n* ?! B& m* j
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Saito, Y. 2010 Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
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1 O' }! _- y0 Y! yVermeulen, L. 2010 Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.2 q% W0 F" S- F6 Z7 b; p/ X/ g
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Youssef, K. K. 2010 Identification of the cell lineage at the origin of basal cell carcinoma.
7 D2 }/ I% `1 U6 d8 SNat Cell Biol& b. O( V/ {0 b# @
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9 b7 B+ A. \% A$ M& q- tClément, V. 2010 Marker-independent identification of glioma-initiating cells.* A M3 c; V- |
Nat Methods
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Boiko, A. D. 2010 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.
, C: z2 R3 k( X1 P6 I4 P# }" Y& kNature9 f, T3 B ~* z# o( F& P
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- \( x `" I8 m. ?$ x9 LNaka, K. 2010 TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.+ ~4 B/ ~! i4 C( y
Nature
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7 {. L D3 p& t, M% b8 a7 z$ VFillmore, C. M. 2010 Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.: N( n# N+ b$ u& d/ K
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J爀猀, M. 2010 Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.8 ~, s7 p; K6 U& s" Q) c+ Y
Proc Natl Acad Sci U S A
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! z+ J# k- H: jLiu, H. 2010 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.& Z" h4 i/ q1 Y- t$ q
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Mizuno, H. 2010 Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.
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Qiu, W. 2010 Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
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Rouet, V. 2010 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.7 Y" y' D& x, b$ s( U* |: h
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/ N4 c5 I: {2 @; H/ Y5 g" vYeung, T. M. 2010 Cancer stem cells from colorectal cancer-derived cell lines.
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. P$ m- v4 m0 N1 pZhang, M. 2010 Selective targeting of radiation-resistant tumor-initiating cells.1 i7 t9 Z) m5 }5 c+ ^9 a
Proc Natl Acad Sci U S A
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Wang, Y. 2010 The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.& f7 d2 A1 W4 ?* w
Science6 w. b ~ e6 p
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Abou-Kheir, W. G. 2010 Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.) Q# K- b# k6 H$ r9 k3 N% b. \
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deCarvalho, A. C. 2010 Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo.
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Hovinga, K. E. 2010 Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.
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Hurt, E. M. 2010 Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.# c/ N k. r9 Z9 w
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7 F1 \( J" s5 E0 q; o& s) bNaka, N. 2010 Synovial sarcoma is a stem cell malignancy.9 S7 k l: ^/ Y7 y- V% d
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$ {: C5 Q X2 D# w2 v$ OStem Cells
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K1 {8 U; g7 f& oStuelten, C. H. 2010 Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel.$ c3 R- x/ W9 `8 Q2 j9 o% A
Stem Cells
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Sunayama, J. 2010 Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
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/ i) o7 ^, m. I5 P. uWatanabe, K. 2010 Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells./ q @' z4 j8 B) B
Stem Cells# e# @) m* L' X8 P4 O' ]0 c# s
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