《细胞》[Cell]12年4月27日出版pdf全文

nero1981

' D; J5 k9 \7 ~1 }+ D+ IVolume 149, Issue 3
+ T9 A5 k4 b4 T) U' V6 i( }' [9 q* X+ TOn the cover: The combined activity of neurons in the brain generates
2 }4 Y: W! S1 yoscillatory rhythms, or “brain waves,” that can be detected by
- [- T5 a3 N+ q. q# B$ p5 Nelectroencephalographic recordings. Verret et al. (pp.708–721) found that these
" q' M# L1 U. e, G- m% D$ tbrain waves, which are represented on the cover by an undulating pattern, are / z/ [5 Q3 s7 Q  S6 J
altered in mouse model of Alzheimer's disease (AD), and the changes are linked 0 X6 }. D* f2 V0 {+ F+ A
to reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
& Q, t' v3 H$ y% xNav1.1 levels specifically in inhibitory interneurons improves oscillatory
7 Y, N( b0 w, r+ T9 m- e  d$ Jrhythms and memory in AD mice, offering a new therapeutic approach for
: @8 G5 k1 R# f/ K) Z  Npotentially treating cognitive disorders. The image was created by Arantxa . v( L" x3 c; c8 }
Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop ( L8 l8 |4 W2 w' H/ ~
(electronic recreation).
: U5 a& G* ?& C( K/ Y[hide][/hide]

menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

谢谢

不倒翁

谢谢

eley

ding~~~

cytobiology

Y的 还是不能查看下载

zorro

回复 cytobiology 的帖子, A6 k+ j5 a7 H
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你的积分等要到50呢

markllq

谢谢% n. {9 d% \/ z: R% C8 Y4 W/ p7 C

191225092

看一看，瞅一瞅。