《细胞》[Cell]12年4月27日出版pdf全文

nero1981

( _, n# `2 X% |) L) v, FVolume 149, Issue 3
( w6 S. n# l7 ^' d! y9 a- h1 a1 ?, YOn the cover: The combined activity of neurons in the brain generates 8 W! w6 \+ k6 }( _- M
oscillatory rhythms, or “brain waves,” that can be detected by
8 s$ {% t5 I: K6 `electroencephalographic recordings. Verret et al. (pp.708–721) found that these 6 B- q) l3 e: H) o
brain waves, which are represented on the cover by an undulating pattern, are
/ {) V8 I, g4 W" z/ I- Kaltered in mouse model of Alzheimer's disease (AD), and the changes are linked ) a: T0 }0 g8 |( Z* c! e
to reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
3 j$ A8 R6 M0 v1 J* CNav1.1 levels specifically in inhibitory interneurons improves oscillatory
( H% e- U* D! h6 O5 F/ @% drhythms and memory in AD mice, offering a new therapeutic approach for ' }3 {$ p9 H3 n: D
potentially treating cognitive disorders. The image was created by Arantxa
) `0 G2 M; T# X" D9 N) f- Z8 L, ~Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop 1 n8 e# Z7 I6 s- x0 h. h# I8 h2 H. d5 V
(electronic recreation).6 c. Z$ V* K9 H# V" y, {
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menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

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不倒翁

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eley

ding~~~

cytobiology

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zorro

回复 cytobiology 的帖子4 P/ J2 Q% a$ A# A4 J

) n/ t& f5 ]: \4 d3 }你的积分等要到50呢

markllq

谢谢
$ {& s  C! a/ b1 @  o

191225092

看一看，瞅一瞅。