《细胞》[Cell]12年4月27日出版pdf全文

nero1981

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Volume 149, Issue 3- Q5 k. g3 F8 Q9 h$ s- ?
On the cover: The combined activity of neurons in the brain generates * X- @4 m- _) i* \+ B6 k: b: Z
oscillatory rhythms, or “brain waves,” that can be detected by 7 p, ]$ M, x% j7 \  C; I+ C. s
electroencephalographic recordings. Verret et al. (pp.708–721) found that these $ F9 t! u$ ^/ H
brain waves, which are represented on the cover by an undulating pattern, are + @% Y4 T5 u8 d- z
altered in mouse model of Alzheimer's disease (AD), and the changes are linked
& }0 n$ h4 H! F' L1 u) _1 G3 rto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
$ i' c9 u+ `* W6 n; Y) @Nav1.1 levels specifically in inhibitory interneurons improves oscillatory
% V/ r4 q; f9 z; q( Arhythms and memory in AD mice, offering a new therapeutic approach for 2 V9 Z9 O6 Y3 o% o9 h
potentially treating cognitive disorders. The image was created by Arantxa
7 A3 [1 ~) N: Y6 `# k9 uEsteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop
. {, x$ f3 m4 H(electronic recreation).
% y/ ?% h  O% }! t2 c" a. {" X[hide][/hide]

menghy

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xiaoheilong

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不倒翁

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不倒翁

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eley

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cytobiology

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zorro

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6 }# b  x/ }0 u& {2 F3 i( p- j) @你的积分等要到50呢

markllq

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191225092

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