《细胞》[Cell]12年4月27日出版pdf全文

nero1981

& f, a  I* g# r8 d5 f$ KVolume 149, Issue 3, p' R, j! X2 ~: B: |3 e
On the cover: The combined activity of neurons in the brain generates
* I' f6 }  z6 W" L- ^8 e) Koscillatory rhythms, or “brain waves,” that can be detected by
4 b5 K4 A- |9 W" }( G1 G. selectroencephalographic recordings. Verret et al. (pp.708–721) found that these
" G& B9 D% P; ?; A8 Ibrain waves, which are represented on the cover by an undulating pattern, are
" f! K9 E4 y( L, o, s: oaltered in mouse model of Alzheimer's disease (AD), and the changes are linked
% `' z  v! S3 f2 Vto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
$ f' r+ {: ~3 ONav1.1 levels specifically in inhibitory interneurons improves oscillatory
1 A3 y/ q9 J4 ]; |" Brhythms and memory in AD mice, offering a new therapeutic approach for
! }2 P! A$ g5 H6 Apotentially treating cognitive disorders. The image was created by Arantxa
6 v4 F) M0 C% E: e; n: C4 m$ dEsteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop
: S' h- z; L5 k; ?(electronic recreation).% r1 f' R& y6 t* K6 C. ~: x
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menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

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不倒翁

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eley

ding~~~

cytobiology

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zorro

回复 cytobiology 的帖子4 g5 h0 Q8 Y  T, o+ z

1 V: [1 g$ H% G& H7 a: ?9 p你的积分等要到50呢

markllq

谢谢
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191225092

看一看，瞅一瞅。