《细胞》[Cell]12年4月27日出版pdf全文

nero1981

, _& E3 N" A  ]. O, N( TVolume 149, Issue 3+ z" y- p( Z0 ^+ k9 ]$ J- X7 j' b
On the cover: The combined activity of neurons in the brain generates . x: {, G( A: Q) Y$ H
oscillatory rhythms, or “brain waves,” that can be detected by   B6 l& m1 ]5 D8 D& Q  L) f+ S. B
electroencephalographic recordings. Verret et al. (pp.708–721) found that these
& x# [8 G3 t3 I! @# O7 b, [brain waves, which are represented on the cover by an undulating pattern, are
- L% g5 T2 Y6 I! laltered in mouse model of Alzheimer's disease (AD), and the changes are linked
/ z  c! `6 T1 b5 a3 Rto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring $ v& J$ P2 _1 z  Z& B6 J
Nav1.1 levels specifically in inhibitory interneurons improves oscillatory
+ R* o4 d! `" Q$ L: o. D8 t. I" g; H+ D) zrhythms and memory in AD mice, offering a new therapeutic approach for
. n, F! x7 V4 B3 ?# [5 kpotentially treating cognitive disorders. The image was created by Arantxa : C: J% k6 G& P# ?, [
Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop 5 C2 C& z0 A8 M* C9 c4 {( _" x
(electronic recreation).3 N; X- L# m: Z4 E
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menghy

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xiaoheilong

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eley

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cytobiology

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zorro

回复 cytobiology 的帖子6 ^5 t+ g6 W% X+ I6 ^6 [) \

7 T) b7 _' y: _7 x6 s, p你的积分等要到50呢

markllq

谢谢7 L8 o: ]& {1 F0 b/ D* ~# m% q9 u; e

191225092

看一看，瞅一瞅。