《细胞》[Cell]12年4月27日出版pdf全文

nero1981

6 J- n2 J9 R/ N) d: nVolume 149, Issue 3
+ v8 M+ r( f5 ?, MOn the cover: The combined activity of neurons in the brain generates - S) y5 _& E# t! r4 f
oscillatory rhythms, or “brain waves,” that can be detected by
" E: F7 O, q; d7 yelectroencephalographic recordings. Verret et al. (pp.708–721) found that these
% H0 Z1 x0 Z: \, p6 F6 K# Kbrain waves, which are represented on the cover by an undulating pattern, are 8 [6 H' b' U) w" v0 F  B
altered in mouse model of Alzheimer's disease (AD), and the changes are linked
5 X$ d0 B, E! o7 V, hto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring / E/ Q) C! L5 @( |' m. t3 r7 N
Nav1.1 levels specifically in inhibitory interneurons improves oscillatory 2 N" L* h, [7 ~6 V2 }% y
rhythms and memory in AD mice, offering a new therapeutic approach for . |6 D0 b9 l8 p
potentially treating cognitive disorders. The image was created by Arantxa
9 ~$ z& f& F8 a4 wEsteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop : c# b; C0 T6 K, y
(electronic recreation).1 T6 l/ v( L9 c  ~& Y' u4 Z
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menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

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不倒翁

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eley

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cytobiology

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zorro

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markllq

谢谢
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191225092

看一看，瞅一瞅。