《细胞》[Cell]12年4月27日出版pdf全文

nero1981

) N( I# y+ L( V0 P
Volume 149, Issue 3
3 R6 y( |: M" \7 F% `6 J0 AOn the cover: The combined activity of neurons in the brain generates % `: e% Z9 B3 F4 M- X
oscillatory rhythms, or “brain waves,” that can be detected by
1 {$ ~) h+ N# X2 Gelectroencephalographic recordings. Verret et al. (pp.708–721) found that these
( ]3 @+ }4 J% j3 U6 |/ w; gbrain waves, which are represented on the cover by an undulating pattern, are 3 y7 g& o% L1 |9 X# a' F; o
altered in mouse model of Alzheimer's disease (AD), and the changes are linked ( x/ ~3 s4 r" o' T  S1 R
to reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
. t/ x6 J/ J' a/ _. LNav1.1 levels specifically in inhibitory interneurons improves oscillatory * g; g! I2 e' c9 V
rhythms and memory in AD mice, offering a new therapeutic approach for
' B+ @8 q# d& o3 ~! X8 @! O: Ipotentially treating cognitive disorders. The image was created by Arantxa
, ?) r6 q( J8 ^) wEsteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop
: e$ P8 ?- q. Y( P0 ^(electronic recreation).8 L& [* q9 l. ^! s7 c, Y8 `# {+ @
[hide][/hide]

menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

谢谢

不倒翁

谢谢

eley

ding~~~

cytobiology

Y的 还是不能查看下载

zorro

回复 cytobiology 的帖子3 Y# v* F0 l, d& [. Z) a

- u* B2 C7 D( v6 [* o- x& S+ e. h你的积分等要到50呢

markllq

谢谢6 S, Q0 h! L0 Z$ e1 w

191225092

看一看，瞅一瞅。