《细胞》[Cell]12年4月27日出版pdf全文

nero1981

) I% z' k7 O$ p( @! @Volume 149, Issue 3
6 T8 @0 \4 p0 W" Q' w( x5 N: jOn the cover: The combined activity of neurons in the brain generates
7 a+ J" b5 x% y4 ]+ Y* koscillatory rhythms, or “brain waves,” that can be detected by
4 s9 I: W4 b9 h9 helectroencephalographic recordings. Verret et al. (pp.708–721) found that these 4 h% D- G$ H, D& y0 G( p
brain waves, which are represented on the cover by an undulating pattern, are
- b1 L2 d) r$ y3 saltered in mouse model of Alzheimer's disease (AD), and the changes are linked
5 n' n/ ^' h& l2 w% W3 H0 bto reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring . V2 D5 W4 l8 F, @, `: C4 E5 f; g
Nav1.1 levels specifically in inhibitory interneurons improves oscillatory   p: G( u! k) l% {( Q
rhythms and memory in AD mice, offering a new therapeutic approach for * K* E9 C8 x1 {: O9 l
potentially treating cognitive disorders. The image was created by Arantxa
; `( a& I* F& l3 A& ~6 _Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop & Q$ {; y6 p" L) X& H! o$ I
(electronic recreation).
4 R+ C! s; ^( E4 U: x4 d[hide][/hide]

menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

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不倒翁

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eley

ding~~~

cytobiology

Y的 还是不能查看下载

zorro

回复 cytobiology 的帖子* e( z' N$ H3 H" ^) ?

! H/ W9 x1 v( G  x9 q2 A7 T, s你的积分等要到50呢

markllq

谢谢/ l  |6 A  Q* k# `

191225092

看一看，瞅一瞅。