《细胞》[Cell]12年4月27日出版pdf全文

nero1981

5 @9 o& I% M2 M. x; T! Y3 \  z( }Volume 149, Issue 38 h+ ~+ _7 _1 f  ~# ]+ ]% {2 }8 c* r
On the cover: The combined activity of neurons in the brain generates
6 D) n) L, i. i6 u3 m& u  Ioscillatory rhythms, or “brain waves,” that can be detected by * S% l: s$ N+ x/ d
electroencephalographic recordings. Verret et al. (pp.708–721) found that these
! O  \) [4 q4 A) \$ N& h: Y) B7 bbrain waves, which are represented on the cover by an undulating pattern, are
: L" ^) L* r! Waltered in mouse model of Alzheimer's disease (AD), and the changes are linked 6 U1 E& N3 N+ j  J6 w, f% b9 J! S
to reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring - J' Z: e. v4 U- v' F
Nav1.1 levels specifically in inhibitory interneurons improves oscillatory
6 q3 X: E% E: q: I2 p) b5 erhythms and memory in AD mice, offering a new therapeutic approach for
1 f, }( e( y- i8 F) D1 epotentially treating cognitive disorders. The image was created by Arantxa 1 A& r, Z  H# T4 M0 E5 {; X
Esteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop 8 u+ U2 V& I9 R
(electronic recreation).
' ~( n( j) d2 n$ A, _! W1 O) U  t7 _[hide][/hide]

menghy

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xiaoheilong

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不倒翁

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eley

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cytobiology

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3 H; n5 v9 U3 }: x你的积分等要到50呢

markllq

谢谢
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191225092

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