《细胞》[Cell]12年4月27日出版pdf全文

nero1981

! C. C3 v; n3 w, @
Volume 149, Issue 37 W* Z, Z8 g* k* v, X
On the cover: The combined activity of neurons in the brain generates / t% U5 q' p0 v- \1 {
oscillatory rhythms, or “brain waves,” that can be detected by & |' U& r7 L  w+ I
electroencephalographic recordings. Verret et al. (pp.708–721) found that these 3 t, @; k6 ?$ Q/ K2 W: e; I" A
brain waves, which are represented on the cover by an undulating pattern, are $ J& a6 K' h9 [
altered in mouse model of Alzheimer's disease (AD), and the changes are linked ! e& t" X# Q! |, v0 d: R  w  q1 j
to reduced levels of a voltage-gated sodium channel subunit, Nav1.1. Restoring
! W. b$ ~+ Q- V' V' P0 I4 n! BNav1.1 levels specifically in inhibitory interneurons improves oscillatory
: P# u# u9 h' s% l- T3 P! g/ wrhythms and memory in AD mice, offering a new therapeutic approach for ( |) Z# t8 _& e% I
potentially treating cognitive disorders. The image was created by Arantxa
; e8 G6 x' k! `* R( C+ a" t% KEsteban (original paintings “Ondas 1” and “Ondas 2”) and Jorge J. Palop / W3 E6 v+ U: M  p2 W9 ^' s
(electronic recreation).. s7 k2 Q/ a; F6 p! u
[hide][/hide]

menghy

谢谢分享！！

xiaoheilong

看看

不倒翁

谢谢

不倒翁

谢谢

eley

ding~~~

cytobiology

Y的 还是不能查看下载

zorro

回复 cytobiology 的帖子+ b& H7 f' V& L( a

$ x- q1 I2 U4 U6 m4 O; ~2 G你的积分等要到50呢

markllq

谢谢3 g/ a8 ~9 l" [5 \# H' B

191225092

看一看，瞅一瞅。