PDF电子书：PROTEIN ENGINEERING （2012）

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. R+ ]& X9 q, F# X8 f6 w% FPROTEIN ENGINEERING2 o: k7 Z; b. w0 x' F
Edited by Pravin Kaumaya
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: h* ^6 @5 ~3 j3 hCopyright © 2012 InTech
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3 X% }/ U, Z+ S0 b1 t- ~4 [Contents
( O' K8 l5 \$ r& J% r7 |- t9 C7 b4 NPreface   IX: j0 F# F# C$ {" u9 f
Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
  W! N' E8 e  m- P( z- s7 XEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 0 K9 ?$ P- C1 i3 r; d2 \$ K) F
Arseniev
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! J5 f7 _# W; [" r9 @Chapter 2    Protein Engineering Methods and Applications   33
' j6 r; P3 [' a) c+ E6 RBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino   Q5 J7 ^; N. k5 B: _4 h
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi+ }. E* v1 \( A# Z/ f+ A
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
, ^+ N2 J; m: Y4 TCandida methylica FDH as a Case Study    75
: i" O1 b" T$ r" r) OEmel Ordu and Nevin Gül Karagüler  d/ h0 F* ~4 }* @! V
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Chapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic 1 h. y! G0 N8 ]: o* p4 x+ [: h* t
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,( o7 {5 r* k! D9 _
K. Scott Weber, David L. Donermeyer,
2 {3 x, @4 ~* y5 j% C' xPaul M. Allen, Roy A. Mariuzza and David M. Kranz, w5 d3 _5 h9 ^0 l0 B. U1 x/ t/ c

9 Q% z$ c% F1 H' U3 ~& _, F! mChapter 6    Molecular Evolution Within
3 y% s# J/ U7 p- M, U: HProtease Family C2, or Calpains    119
0 d+ M5 s/ D% R' o6 cLiudmila Lysenko and Nina Nemova
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( O; x2 M; L5 a9 U! O# {Chapter 7    FN3 Domain Engineering   145
, x# E" P  i' ]/ p9 Y/ z5 H! YSteven Jacobs and Karyn O’Neil
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Chapter 8    Engineered Derivatives of+ v- p. W6 J3 M; \8 a9 m
Maltose-Binding Protein   163- u: F: Q- D) r' t& r$ @
Paul D. Riggs
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VI     Contents
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0 Q; F5 ^6 E! Z& J2 JChapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
4 n+ k5 C6 n7 RProtein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky- p. Q( w% M% l/ p8 N, J" e4 F
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
  C* X% n' G5 v3 |Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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, i# O5 P5 l- d" i, a2 ?/ c1 ~Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
- {! Y) _9 c" n5 B7 Z+ w% QAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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Chapter 12    Generation of Xylose-Fermenting, g' U3 R9 u( m( }; S! a$ j
Saccharomyces Cerevisiae by Protein-Engineering    2918 T2 w6 x5 `4 O% h7 S
Seiya Watanabe and Keisuke Makino6 P: u6 f+ H( b" Z- w  R; C/ U
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Chapter 13   In Silico Engineering of Proteins3 {% I6 A3 w$ ]$ @3 w
That Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela 9 z# G) [# p5 C) W6 `# C
Wimmerová* o) ~9 G" @( s3 ~* X# D/ J

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