PDF电子书：PROTEIN ENGINEERING （2012）

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PROTEIN ENGINEERING
3 U2 O: Q9 {; m  u  v* gEdited by Pravin Kaumaya
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Copyright © 2012 InTech
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9 k$ I5 @+ ]$ {; S) Y0 ~9 VContents; O7 w; H/ Q# Y7 w4 @
Preface   IX5 \8 A+ @, A5 B* [) C
Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1  M, g! ~3 r& [$ u, c8 H; j0 I+ x
Eduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 4 w# ~& q+ d+ M* z2 A, u0 y
Arseniev
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: k+ W6 s% U3 {& SChapter 2    Protein Engineering Methods and Applications   33; Z, ^1 y* h+ Q" w! D
Burcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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- t% c7 e0 A& r6 R) hChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
, _+ H3 |6 H7 |7 |* Q6 uAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:- [1 Q8 z. e" U7 |1 c
Candida methylica FDH as a Case Study    75
0 @  y3 X4 T% UEmel Ordu and Nevin Gül Karagüler1 ?3 M/ N. Y9 ~
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Chapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
  x4 P! p3 a0 J7 I9 j* ~+ YTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,6 s+ K! Y1 }1 T( w! `4 J
K. Scott Weber, David L. Donermeyer,# u/ s! |2 N$ t& D
Paul M. Allen, Roy A. Mariuzza and David M. Kranz
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" G7 ^3 O. |! l5 ^' U/ IChapter 6    Molecular Evolution Within
7 D& p# o9 Z$ A% a. q+ }$ \% l7 @Protease Family C2, or Calpains    119) n. v' ?: L0 b  [& E2 \2 l. h
Liudmila Lysenko and Nina Nemova
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Chapter 7    FN3 Domain Engineering   145! |+ I( M. m5 Y
Steven Jacobs and Karyn O’Neil
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/ s" f6 C1 I) N( Y* h( HChapter 8    Engineered Derivatives of
, O5 a- D7 p4 \- bMaltose-Binding Protein   163
) I$ c+ @8 b6 `6 Y" S1 _0 ePaul D. Riggs
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VI     Contents
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Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
6 y4 W' D3 O+ n- IProtein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
7 G" c& O& i* s! i* D5 [% n9 BShu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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# _* v1 f+ ^( V! A  [1 xChapter 11    Protein Engineering with Non-Natural Amino Acids   253
# C/ j. c: \7 E0 w9 JAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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, I7 `! ~+ A4 ]1 m( `0 rChapter 12    Generation of Xylose-Fermenting* V6 Q, f6 {& r7 i) t4 Y
Saccharomyces Cerevisiae by Protein-Engineering    291
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& `% ]3 J7 ]8 A5 _Chapter 13   In Silico Engineering of Proteins
* Z9 T# S' p" tThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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