PDF电子书：PROTEIN ENGINEERING （2012）

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PROTEIN ENGINEERING
! b* k3 e% t0 f4 V& QEdited by Pravin Kaumaya
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Copyright © 2012 InTech, d% n5 X. j  H7 f7 D! `: B$ R5 w

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Contents7 F% y! Q! W9 q9 y$ }
Preface   IX
0 @( [+ c: E# J& G7 F& `7 GChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
' T6 Z; d0 ^1 r: cEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. $ i: i4 _# F! V3 S4 |
Arseniev
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& Z% U- \3 ?- X7 k' hChapter 2    Protein Engineering Methods and Applications   33
8 `: M* v; D) c  H, `Burcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar( t$ P% e; }2 W9 X# v2 s/ p+ Z  |9 d

) i- h9 F; e  u; E$ a/ SChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino ! G: a1 {9 B. A: B+ C$ L- H
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi
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! m, U1 e3 K# ]) oChapter 4   Protein Engineering Applications on Industrially Important Enzymes:
: }9 F2 C6 v: s  eCandida methylica FDH as a Case Study    75
% x& y2 W. v2 DEmel Ordu and Nevin Gül Karagüler
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Chapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
- G4 P1 b# p) i% X4 g, vTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,3 K# H$ u$ y. K2 G% t- Y
K. Scott Weber, David L. Donermeyer,
( N2 }- M/ W+ ^0 SPaul M. Allen, Roy A. Mariuzza and David M. Kranz. J% e( j  T2 _
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Chapter 6    Molecular Evolution Within
1 g# i, U; L( P: y2 a" B1 LProtease Family C2, or Calpains    119
9 B1 J  m( j0 y# |, z8 mLiudmila Lysenko and Nina Nemova
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2 Q; c! B# s0 C* UChapter 7    FN3 Domain Engineering   145) F! |3 O" E  _" v; c9 U" f# C
Steven Jacobs and Karyn O’Neil
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Chapter 8    Engineered Derivatives of/ [' u) O: x7 ~, }3 C* s
Maltose-Binding Protein   1630 v; k) @1 u, p  Z0 C* u- f
Paul D. Riggs8 b  i% o+ r! _/ h

& ?% ]: c) W# AVI     Contents
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Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based # l9 G4 `% k: t1 ^* _+ K, K: I1 K
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky4 }1 ^  G: W' J3 t

5 z% d6 p0 b1 W) TChapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
& i% k6 P$ s% a8 qShu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu/ B1 p- `9 N- S

; `$ L( Z1 S; P. ?0 SChapter 11    Protein Engineering with Non-Natural Amino Acids   253
2 k9 o' O% G" [! C% V1 UAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein3 R6 j, Q/ h" T: ?
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Chapter 12    Generation of Xylose-Fermenting2 ?1 a% O3 D) }
Saccharomyces Cerevisiae by Protein-Engineering    2912 D9 ^& ?) ~- f* x6 R2 Y  Q
Seiya Watanabe and Keisuke Makino
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2 X& c. \# W- j9 wChapter 13   In Silico Engineering of Proteins4 Z2 E5 w5 [7 O  T# b% F
That Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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