PDF电子书：PROTEIN ENGINEERING （2012）

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6 J# b; p. M; g# c& }- iPROTEIN ENGINEERING& @6 D$ q( Z( ^
Edited by Pravin Kaumaya
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2 F. o3 ^, c+ e$ vCopyright © 2012 InTech+ a, U% p4 g( {3 N

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' l+ @$ {7 N8 O/ v9 t& g3 kContents
3 u6 ]; @/ b' M2 v, x) ZPreface   IX: n# w7 I8 p1 K% |
Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1# A# i, J" f8 y, K2 Y% J3 B* t+ m
Eduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 3 q5 i3 P9 u& h) T7 {: V: {
Arseniev
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Chapter 2    Protein Engineering Methods and Applications   33
- K" q9 s. e/ WBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar6 V) |, I- N" x) ~% r' S5 t
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
9 ]% A4 W( m$ N/ e8 XAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi6 k, f. r( }) I4 S! V# d1 K) @! }& |

) n' H* l' ]) `! c  z9 y8 x/ KChapter 4   Protein Engineering Applications on Industrially Important Enzymes:
/ w% X- u$ O) [# r- YCandida methylica FDH as a Case Study    75
; }6 X0 }& u/ y7 i- MEmel Ordu and Nevin Gül Karagüler
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; F4 [9 N5 F3 l' M# E' eChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic 1 Y* z+ y1 S  f; Q# U! J& o
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
3 S2 V1 ^8 g/ uK. Scott Weber, David L. Donermeyer,9 A2 s8 A5 H5 E, k9 ~. N2 ^
Paul M. Allen, Roy A. Mariuzza and David M. Kranz6 w9 l0 w% i, I; M, {

. ^8 n1 R. V$ h# T5 B+ C4 HChapter 6    Molecular Evolution Within) `# Z" b8 P, v0 P5 l$ u5 h1 K! {
Protease Family C2, or Calpains    119
& L: c' E8 P( z5 p* S, jLiudmila Lysenko and Nina Nemova
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Chapter 7    FN3 Domain Engineering   145
( R. f* {) n# ]% NSteven Jacobs and Karyn O’Neil  e5 x, P8 e4 w6 T) D
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Chapter 8    Engineered Derivatives of6 q1 b4 u" Q2 _) e
Maltose-Binding Protein   1633 N+ x3 [& f( T
Paul D. Riggs
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  z  n" t4 O, U/ ]" B& C9 [VI     Contents
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5 c* f% e' n# {6 BChapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
) u% Q5 i; A% p$ ]* s7 }Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
' A( p3 i* t/ n: sShu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu& `. Y4 q" X& T2 s1 Q: f

3 u: `0 g& v. a* }) j& W$ v) z$ J0 eChapter 11    Protein Engineering with Non-Natural Amino Acids   253
3 z9 i0 {" g# ?5 Y) Y! BAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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0 `, y$ \' C3 |5 H1 s$ k8 bChapter 12    Generation of Xylose-Fermenting, `$ C8 S# p% J4 O
Saccharomyces Cerevisiae by Protein-Engineering    291
$ R# g+ @, E% }Seiya Watanabe and Keisuke Makino9 O6 h8 \) T1 k* D; y

% x) e0 B8 M6 z: nChapter 13   In Silico Engineering of Proteins! y5 I' A) n" F
That Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela ' N' Z. M3 Q: D: ^
Wimmerová1 C4 x: C* X  v

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