PDF电子书：PROTEIN ENGINEERING （2012）

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$ R) g& n+ z# RPROTEIN ENGINEERING
# `2 W5 w$ i8 R: g5 w! j0 YEdited by Pravin Kaumaya
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Copyright © 2012 InTech4 W* t" f2 w2 i. k1 G% n# I

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5 o9 ~% ?2 f$ {+ K! t' KContents% X9 v4 H4 }* P0 t) W
Preface   IX
( U8 y# ~2 x" \2 _Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
* m; c; i' l. ?+ X, eEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 7 S" B  S( h  k
Arseniev
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! u+ r7 ~7 [7 |Chapter 2    Protein Engineering Methods and Applications   33
; R7 p+ f. o" ~4 ^; J. L8 P- }Burcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar4 C$ t# `' Q7 T5 z0 \: g

  x. k0 E- F+ _: c- d6 dChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino 0 B! p8 }$ Y6 S% {- i( @
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi( u* t- U2 {8 x1 }8 e
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
: @# \: m( [; a% H) ZCandida methylica FDH as a Case Study    750 s% @7 B9 t: x; O" K
Emel Ordu and Nevin Gül Karagüler
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7 F7 ]6 b7 y1 r% I! t$ ZChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
! M# z/ d* }5 ~1 b% R* F+ sTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,1 Q- w0 D8 c& b9 J1 r6 k1 d4 i
K. Scott Weber, David L. Donermeyer,, m5 N. ^% x6 h; S+ H
Paul M. Allen, Roy A. Mariuzza and David M. Kranz1 T# `. J$ M  ?5 Z- e0 `4 t/ `. b
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Chapter 6    Molecular Evolution Within4 K; E% e; n% y; _+ ]( }3 _1 a1 {
Protease Family C2, or Calpains    119
/ X! u$ i! l+ h0 qLiudmila Lysenko and Nina Nemova
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* S+ X" B: I* NChapter 7    FN3 Domain Engineering   145
: X0 |) @) U6 x4 i. @6 }Steven Jacobs and Karyn O’Neil( I+ d  Q/ |, N7 N8 H0 U4 G
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Chapter 8    Engineered Derivatives of
) }/ Q* G9 J- l# GMaltose-Binding Protein   163( ]' [2 u, V% g, |
Paul D. Riggs! J: n1 a& K) C2 f0 Z

2 i' e0 I& h# VVI     Contents
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3 C/ }! T1 E( a! c* N# O" g" }Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
1 l" P  H& r- K' H/ ?Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
8 N3 L) o0 L. D" P" E  ^: H! WShu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
0 ~$ s! v) K& f7 }# l9 U8 A/ jAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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  X% @4 z1 y: J, q+ Q# lChapter 12    Generation of Xylose-Fermenting: f7 \$ J" K, q! o1 Z% `: ?$ u
Saccharomyces Cerevisiae by Protein-Engineering    291
7 k, j1 r8 i  C, ]1 j. b1 b' wSeiya Watanabe and Keisuke Makino
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1 K6 [, B( J& }1 d' u' T7 CChapter 13   In Silico Engineering of Proteins
* T8 X' o# e6 gThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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