PDF电子书：PROTEIN ENGINEERING （2012）

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+ w" C3 b5 z: f6 {4 @PROTEIN ENGINEERING
3 Z' c/ A- y) |Edited by Pravin Kaumaya, f" ]. V' X* |9 k/ Y

& Z+ \1 j0 r: [, rCopyright © 2012 InTech
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' E$ o" L' a9 Z, cContents- r& X& c# {' I' }
Preface   IX
  A8 |1 [' w$ L. b5 U3 qChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
6 I( B+ |; \, @- LEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 9 W5 ?7 ], g# Q% B
Arseniev2 h$ l2 B3 x4 `& X/ k/ F

$ t& s% l/ G+ ~Chapter 2    Protein Engineering Methods and Applications   33
( ]9 ~" N8 ?9 e0 ~9 r0 A4 VBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
1 g' r" f4 ~% y7 W& iAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi2 q- m, b; o! c! s8 d, e
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
+ R+ P" J9 t/ j- a  }/ j9 U5 rCandida methylica FDH as a Case Study    75
* o. O0 A- ^1 ~7 nEmel Ordu and Nevin Gül Karagüler
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( J( U7 [( X( ]" eChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
9 m3 K- @" ~" YTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
0 p8 Y0 a& i, H* s  LK. Scott Weber, David L. Donermeyer,* ~! \" R* T* b( g% K+ u
Paul M. Allen, Roy A. Mariuzza and David M. Kranz
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Chapter 6    Molecular Evolution Within2 [3 v, j4 j6 c& t9 n
Protease Family C2, or Calpains    119+ Y' N# M0 R/ u7 I& L. a
Liudmila Lysenko and Nina Nemova# i7 y6 H3 N! |8 c0 ]) R& I
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Chapter 7    FN3 Domain Engineering   145
3 I: Z5 t0 ]  F* R0 d4 K1 GSteven Jacobs and Karyn O’Neil
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0 J0 c; S( H0 ?3 h, Q, PChapter 8    Engineered Derivatives of
$ y0 i: O6 d; e7 x+ ^Maltose-Binding Protein   163
9 m2 v2 m8 h) `+ FPaul D. Riggs
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/ w. w1 ?0 ^( y- X9 |3 [& nVI     Contents
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5 `+ D3 C& F2 C1 pChapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based ! W' t4 X: _2 G6 _
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky4 m3 d! I7 N1 h# [8 {6 C3 {1 \
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207) S/ M. f- {- x/ y7 O3 J
Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
2 A4 A- b( r' S' |Aijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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Chapter 12    Generation of Xylose-Fermenting3 _* _- [5 B. \: ]1 l
Saccharomyces Cerevisiae by Protein-Engineering    291
$ m; B* u2 B  ?& ]) w- j& USeiya Watanabe and Keisuke Makino
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Chapter 13   In Silico Engineering of Proteins
0 ?( a7 z4 o2 b) J- dThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela ( ~6 C& x8 d+ X, D: t; m
Wimmerová
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