PDF电子书：PROTEIN ENGINEERING （2012）

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3 }2 x$ p/ a/ e( ?+ e# ]- rPROTEIN ENGINEERING
, ?. C8 N6 H/ P- V& _$ z, N: XEdited by Pravin Kaumaya- D, |  n$ h  d2 y5 W7 y
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Copyright © 2012 InTech
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: i) i+ r! ^0 Z  `4 WContents# n0 W' |! p: ]. |
Preface   IX
2 p: ^5 C/ ]& m* }$ d$ c+ zChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1$ V- ?- D$ [& J: _! K5 s
Eduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 3 |: [& S1 q: P( L% Y
Arseniev+ I* w* h/ H6 I( n) [! r% i4 R

; A, i- m" B7 ?" {( n5 EChapter 2    Protein Engineering Methods and Applications   33
2 x7 w+ Z& q6 ?$ F  e/ |" D: GBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
0 @: p1 C, ~" kAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi& I/ i0 e% b" K
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
8 v* |8 h/ s) K3 }0 }Candida methylica FDH as a Case Study    75, W- F4 L& z( g# k  i& M% f
Emel Ordu and Nevin Gül Karagüler
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- d, E* \8 v5 f, Q& `' M/ `Chapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic + h6 s& Q- ]& m4 G( M/ v
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
9 M; ?. ?6 D5 x5 q( L: @7 lK. Scott Weber, David L. Donermeyer,
6 T# O' }: W, V0 }- Z! m# G9 p- \Paul M. Allen, Roy A. Mariuzza and David M. Kranz
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Chapter 6    Molecular Evolution Within
! z) w. Z8 S$ ~6 C1 v0 qProtease Family C2, or Calpains    119
& g4 o* z+ ?2 o" DLiudmila Lysenko and Nina Nemova( Z0 f2 V4 Y9 N1 v% h
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Chapter 7    FN3 Domain Engineering   145
  ?& L. @8 V5 R( k( P1 FSteven Jacobs and Karyn O’Neil
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Chapter 8    Engineered Derivatives of& M3 n/ X' q, I" C
Maltose-Binding Protein   163
$ r3 }: }2 a4 R6 a+ p4 GPaul D. Riggs; _0 J  G$ j3 d6 F5 s' _

& {0 o& j, G2 _% J9 _, K: T( b7 A0 pVI     Contents
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: h: K0 W7 \( I2 h4 z) k) l- LChapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based # d3 D/ ~& N! e
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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/ e1 i# ^! _8 VChapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   2071 m, I4 m- M- o2 q
Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu0 o) O& X$ A; X! O, K: X

1 o- ]1 o5 T! F1 q! \' V- rChapter 11    Protein Engineering with Non-Natural Amino Acids   253
& h! r0 z+ f; v: Z* m( L9 ZAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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Chapter 12    Generation of Xylose-Fermenting
8 |( e: k8 ^! D1 ]2 G( J7 nSaccharomyces Cerevisiae by Protein-Engineering    291' F, C5 ?, Y3 \( m% t+ H$ g
Seiya Watanabe and Keisuke Makino
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4 u* j: S7 t( n6 E& w. }) ]. Y: G. ZChapter 13   In Silico Engineering of Proteins
* u; D& a; o3 q2 x5 a4 eThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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