|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
: S- q& F& f% V/ _* Z* [8 u
 / G8 T9 G9 E, v, Q" y; \
Volume 25, Issue 3On the cover:
3 ]/ q) [4 _ h, j) MEpidermal growth factor (EGF) induces fast and efficient mitotic progression,
: `% n+ i0 h% u7 A9 R' d0 u7 Gparticularly in cancer cells, by accelerating centrosome separation. Thus, a : g9 L4 X. G/ ?
HeLa cell treated with EGF proceeds faster through mitosis (left path) than a d5 g9 N) r3 R6 O# [# f
cell left untreated (right path), as visualized by confocal microscopy.
* {" r( q) l, M- w4 |0 h3 iH2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
5 X F% [/ }. z4 j% M9 ]7 \8 d( Qenvelope. For more information on the effect of EGF on centrosome separation and & @5 E" }0 B' S7 A: Z
mitotic progress, and on how this may relate to cancer therapeutic strategies,
0 S. b: I: U lsee Mardin et al., pp. 229–240.
& @: ~$ K' b" N( Q# G7 B' c; u" a2 U, y% m
|
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-21 22:33
