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Volume 25, Issue 3On the cover: 5 |( t! r' g( g; ]* H
Epidermal growth factor (EGF) induces fast and efficient mitotic progression,
6 c$ O; V; Y2 Cparticularly in cancer cells, by accelerating centrosome separation. Thus, a
. u+ K6 ?1 @+ c- e; x! }. U4 Y4 kHeLa cell treated with EGF proceeds faster through mitosis (left path) than a
# U/ l* S( S( Fcell left untreated (right path), as visualized by confocal microscopy. / M" A- y; u2 l4 e, a
H2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear ' i- k$ v6 V( p7 F% }+ ]
envelope. For more information on the effect of EGF on centrosome separation and
+ r( h$ T8 X, V0 x; \+ tmitotic progress, and on how this may relate to cancer therapeutic strategies,
3 ]) [; u- V3 ]. b; {6 G$ ?) Asee Mardin et al., pp. 229–240.
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发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
