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4 P) R) g# f, p! n9 C* [Volume 25, Issue 3On the cover:
, T( Z2 r3 B; U$ a" P% }. f/ A0 KEpidermal growth factor (EGF) induces fast and efficient mitotic progression,
6 I8 v2 B( T% U; W9 mparticularly in cancer cells, by accelerating centrosome separation. Thus, a 1 b/ m2 G0 P1 f+ h
HeLa cell treated with EGF proceeds faster through mitosis (left path) than a # o' t U) q: W5 v( e& M
cell left untreated (right path), as visualized by confocal microscopy. ! h4 J6 T% L. ~# W" h
H2B-mCherry (red) marks chromosomes; eGFP-laminA (green) marks the nuclear
, P& y$ |3 s5 K& A; Wenvelope. For more information on the effect of EGF on centrosome separation and
# Z- W- ?4 ?# |- _2 a8 p7 p% {9 ?mitotic progress, and on how this may relate to cancer therapeutic strategies,
2 m1 n' p. N, C) jsee Mardin et al., pp. 229–240.
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发表于 2013-5-21 22:33
发表于 2013-5-22 10:29
