|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
9 ^: I! x% D! H" z; j
. W+ [% ~$ W" `) O+ IVolume 78, Issue 4On the cover: Neural networks control
) Z j/ c! `* ~intrinsic encoding of the circadian clock. Circadian pacemaking in the
. I0 J6 t, |) J' d0 V6 z! f& asuprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and
, U! i) v) y5 q/ n( B8 aintercellular properties, with the latter still poorly understood. In this issue
7 P3 m* h' }, ^0 i! _. R. rof Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level
9 r& Q& }5 d# k3 hencoding of circadian time, showing that specific activation of Gq-Ca2+ axis in
- [0 H$ u4 T# d1 L! Trestricted SCN neuronal subpopulations reprograms encoding of circadian time by + C7 o7 h" g3 F' m' N, |
the entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic & f7 W" k# ~, `* o1 l7 |
connectivity. Concept by Marco Brancaccio; cover illustration by Joanna
% t$ o% Q; L. E0 g7 W/ UWestmoreland.
+ I$ Q) }1 Q1 L; |1 Q
# n* t5 O# ?* D1 a, Y2 G+ o! d* p8 R |
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2013-5-23 23:46
