2013-5-22 Neuron

nero1981

游客，如果你要查看本帖隐藏内容请回复

" e4 D3 b( }  l: W * R) Q; J4 S8 N+ K. L
Volume 78, Issue 4On the cover: Neural networks control
3 P5 ]6 c0 G( q! a& j7 @5 M5 y$ c) r# ointrinsic encoding of the circadian clock. Circadian pacemaking in the
5 r6 [; D1 ^1 o! k/ g. B# asuprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and
" \% g# N: M" A  C% L9 H4 R9 aintercellular properties, with the latter still poorly understood. In this issue " b0 Q' K1 N( ]  S; t$ w
of Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level : {1 f. n! B+ i2 B# G
encoding of circadian time, showing that specific activation of Gq-Ca2+ axis in , r, F$ `, }7 `* F" k, S+ R( B
restricted SCN neuronal subpopulations reprograms encoding of circadian time by 2 [- t6 k% J0 c3 d3 V9 _4 T
the entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic # u2 j: L/ n$ }1 F; i1 P  ]0 S- \
connectivity. Concept by Marco Brancaccio; cover illustration by Joanna ( e. I4 i/ O1 V* o2 d) ~& Z
Westmoreland.  d5 V" q' }3 o
% P3 E# I# C7 K1 }0 q7 Y