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2013-7-26 Science& N3 D9 b1 r+ T& [* m2 F2 o' [4 R

$ E# x+ ^# Z1 b& O! T$ DCOVER Immunostained fluorescence microscopy image of memory
" r6 E+ j( Z7 [* a3 Kengram–bearing cells (red) in the dentate gyrus of a mouse hippocampus (image
# g5 z2 W1 {* U9 J$ Q5 G9 n: B! G" lwidth: 1.5 millimeters). These cells were genetically tricked to express the # Y7 l4 `8 j& F* C
protein channelrhodopsin-2 during memory formation, thus becoming responsive to
* t2 t6 Q- t9 t3 Slight stimulation. When the cells were activated by light, the mice 1 Y9 f4 j; ?; p, J
simultaneously associated a genuine memory with an undesirable event (a foot r: T2 E* `% a0 U4 A& r
shock) to create a new but false memory. See page 387. Image: * U6 U6 ]3 M, T+ ~% a" z+ Z
Xu Liu and Steve Ramirez
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