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2013年12月5日 Cell/ k1 ?. e# Z$ \5 o) o
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5 December, 2013 Volume 155, Issue 6; m" y2 v$ `! y+ _
On the cover: The nuclear pore complex
2 N0 `: x3 Q) d: i* r( R4 n3 l: P& O(NPC) is a large multisubunit structure that regulates the exchange of - S) J. S% A9 @) z4 e% J$ s7 E
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al.
( M) E# v" q% H7 M& `(pp. 1233–1243) use an integrated approach to establish the blueprint for the & [( g- W2 g. m; u% U3 M! l
structure of the NPC scaffold in humans and explain how changes in the diameter
- z2 T; d' s" g* c( m* X! ]of this scaffold enable the transport of large cargoes. Cover artwork by Khanh
; L/ q: S1 o9 {) THuy Bui. Original photo by Alan Levine. k' I3 X3 s4 ?3 A' V; x
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发表于 2014-1-1 23:59
