2013年12月5日 Cell

nero1981

2013年12月5日 Cell
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5 December, 2013 Volume 155, Issue 6
; \* X4 h3 K7 y+ h  T, \6 EOn the cover: The nuclear pore complex
7 P4 e1 g. `) s  `8 |& Q(NPC) is a large multisubunit structure that regulates the exchange of ) N% n% g0 R, D% f4 D
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. $ I2 |/ v$ Y# @6 U! f  A0 o2 i
(pp. 1233–1243) use an integrated approach to establish the blueprint for the
4 J7 o% V# G( n# Ystructure of the NPC scaffold in humans and explain how changes in the diameter 1 |# u# ]4 T: x8 b' Y
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh
6 `2 A. P& Z+ s+ Z4 P. [Huy Bui. Original photo by Alan Levine.7 g9 E0 R) _+ \! \
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