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2013年12月5日 Cell
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5 December, 2013 Volume 155, Issue 6
7 P- S9 L% C5 z2 COn the cover: The nuclear pore complex 2 T% J0 ?' y! B/ ]
(NPC) is a large multisubunit structure that regulates the exchange of
E( \+ r) I/ S+ wmacromolecules between the nucleus and the cytoplasm. In this issue, Huy et al.
t; n S. }- {( c# L* ~(pp. 1233–1243) use an integrated approach to establish the blueprint for the ( i& V K. I$ _8 o
structure of the NPC scaffold in humans and explain how changes in the diameter e ~5 h* g* R6 _: f/ g
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh * p/ Q! W I6 F& p% R
Huy Bui. Original photo by Alan Levine.
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