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2013年12月5日 Cell
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5 December, 2013 Volume 155, Issue 6' G: M4 ]9 v, v, p7 a
On the cover: The nuclear pore complex + V$ _0 t6 e: W9 q( ]
(NPC) is a large multisubunit structure that regulates the exchange of
/ c- O6 A( `( g) ~macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. ! P2 N) F+ G, \
(pp. 1233–1243) use an integrated approach to establish the blueprint for the
0 V) F C) q2 R; Sstructure of the NPC scaffold in humans and explain how changes in the diameter
4 n7 A/ _* r/ C3 Vof this scaffold enable the transport of large cargoes. Cover artwork by Khanh * V* o# I* l" J# \3 p' a" O
Huy Bui. Original photo by Alan Levine.
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