2013年12月5日 Cell

nero1981

2013年12月5日 Cell
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. g! C) b3 u9 p4 O7 f3 ]5 December, 2013 Volume 155, Issue 6
7 U; r! R1 P+ S( m2 r8 y' ]- fOn the cover: The nuclear pore complex
! c1 Y% J% w& A, V& w6 B* T5 z) L(NPC) is a large multisubunit structure that regulates the exchange of 5 o5 L$ F+ e2 M8 \; I) x" s
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. % f. I1 b) f6 @& C$ ^
(pp. 1233–1243) use an integrated approach to establish the blueprint for the 1 ^5 F* N3 v5 N" K! j6 ]* w/ ~
structure of the NPC scaffold in humans and explain how changes in the diameter . L2 y% b  K* P! o
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh * ?6 }# g& D' g9 H! T# ?& ?5 A
Huy Bui. Original photo by Alan Levine.0 }! r; c, G. w3 O9 K, i0 p

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