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- 积分
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2013年12月5日 Cell
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$ p ?* \, c7 J5 E7 m7 h, W5 December, 2013 Volume 155, Issue 6; l5 R! R4 M! l2 r5 Q+ |
On the cover: The nuclear pore complex 6 ]' T0 K+ c! U1 t3 k# k+ R
(NPC) is a large multisubunit structure that regulates the exchange of
2 N: H$ R: l$ W. U" T Amacromolecules between the nucleus and the cytoplasm. In this issue, Huy et al.
' C, u( Q" D4 C(pp. 1233–1243) use an integrated approach to establish the blueprint for the 8 S7 H# M! `, ^5 W" S( y
structure of the NPC scaffold in humans and explain how changes in the diameter # P7 E9 r6 `0 X) l i: L
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh
, j, \+ K' @' U% @* w, qHuy Bui. Original photo by Alan Levine.
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