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2013年12月5日 Cell( G7 g: a0 I, M. j$ n
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5 December, 2013 Volume 155, Issue 6
6 n2 P( d2 \4 b% o8 f. rOn the cover: The nuclear pore complex
! _) o; A- N' ~! z8 r3 T(NPC) is a large multisubunit structure that regulates the exchange of " y- k- l. [8 v5 |/ W
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al. % \& C2 n# _, W9 t( I
(pp. 1233–1243) use an integrated approach to establish the blueprint for the
1 [ I& e! Q j: jstructure of the NPC scaffold in humans and explain how changes in the diameter ' C' L# W7 \3 u! W D: x; m- j
of this scaffold enable the transport of large cargoes. Cover artwork by Khanh
) ]0 g6 I& f; b9 B9 w. lHuy Bui. Original photo by Alan Levine.
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发表于 2014-1-1 23:59
发表于 2014-1-3 21:35
