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2013年12月5日 Cell
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5 P/ u7 u# y# }) i4 G5 December, 2013 Volume 155, Issue 6
& G8 X. l5 f% ~# fOn the cover: The nuclear pore complex
8 Q+ w" i; N8 h- D! z- g9 P' x; s(NPC) is a large multisubunit structure that regulates the exchange of # B, D2 }& P5 ?% z, o# T
macromolecules between the nucleus and the cytoplasm. In this issue, Huy et al.
5 s. j% X7 q/ u(pp. 1233–1243) use an integrated approach to establish the blueprint for the 0 x5 }; ~" T H3 w5 \1 ~: F. Q1 a* }1 o
structure of the NPC scaffold in humans and explain how changes in the diameter
3 S: {( G* t( x1 m2 C: wof this scaffold enable the transport of large cargoes. Cover artwork by Khanh
" S2 U6 e J3 I) BHuy Bui. Original photo by Alan Levine.
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发表于 2014-1-1 23:59
