Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.1 c, |5 U7 {! G2 H& T. U
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The deepening of our understanding of normal biology has made
4 J2 J& V$ e( r* V+ Uit clear that stem cells have a critical role not only in the generation of complex8 G# v3 B; x4 j5 z$ N
multicellular organisms, but also in the development of tumors. Recent
* u. H* ~. Z* j0 L+ u9 Ufindings support the concept that cells with the properties of stem cells are integral* H  h, r$ l. N# G
to the development and perpetuation of several forms of human cancer.1-3 Eradication
% I6 p1 B9 y0 u% }( Nof the stem-cell compartment of a tumor also may be essential to achieve stable,) d& \1 q( [7 T. B) f+ V
long-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of' ]' v# r: G9 y; L. a" y6 A0 ?
the properties of stem cells have made specific targeting and eradication of cancer" ~4 ?2 U1 O* E" z2 ~0 [7 r
stem cells a topic of considerable interest. In this article, we discuss the properties: W) c5 @4 ?% v! |, E, V) ~
of cancer stem cells, outline initial therapeutic strategies against them, and present
" Z& R) ^6 A5 y* @challenges for the future.
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efool

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Fischer3

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ahmusht

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Chris

like it : J9 {9 q' s8 Q# t4 ~! T1 {
thanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good