Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.
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The deepening of our understanding of normal biology has made
, Y8 E+ P0 q5 ~1 o- j$ Ait clear that stem cells have a critical role not only in the generation of complex$ e! e6 s7 @. h$ N" l+ G
multicellular organisms, but also in the development of tumors. Recent
& O- |  b& ?1 c0 |* Hfindings support the concept that cells with the properties of stem cells are integral7 O4 P, H' H/ ]1 V! T$ T. n& ]; G+ F
to the development and perpetuation of several forms of human cancer.1-3 Eradication. k6 X' t3 K7 \9 w) R
of the stem-cell compartment of a tumor also may be essential to achieve stable,
$ w' t5 i7 @4 R& [% Olong-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of* K5 M* V1 Y! P7 Q, ]
the properties of stem cells have made specific targeting and eradication of cancer
+ n& ^$ B: }  @( C; h" x' }; Hstem cells a topic of considerable interest. In this article, we discuss the properties
4 [- j; g# r& O. \of cancer stem cells, outline initial therapeutic strategies against them, and present
, Q+ `2 g# {5 ?5 ~/ }' rchallenges for the future.
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碧湖冷月

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lalala

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温暖暖

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dypnr

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wq90

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ines

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biobio

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剑啸寒

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dd赤焰

说的不错