Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.0 E9 R- O' M+ S& \: X
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The deepening of our understanding of normal biology has made
) U$ H2 b/ i, m- F$ h8 q2 C! xit clear that stem cells have a critical role not only in the generation of complex
5 _" ^" p* ~9 {1 [multicellular organisms, but also in the development of tumors. Recent9 s" E1 ?# q8 P' d3 R
findings support the concept that cells with the properties of stem cells are integral
  i2 l$ e5 p$ E0 E9 pto the development and perpetuation of several forms of human cancer.1-3 Eradication" L! x: X% E5 W. J! Z5 l. I$ F
of the stem-cell compartment of a tumor also may be essential to achieve stable,
- Y" m* A3 h+ `3 along-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of
" K' \. D- D) s1 a- Q8 Q+ W7 O9 Y( kthe properties of stem cells have made specific targeting and eradication of cancer
1 l8 F, U0 c5 T# o, t, Nstem cells a topic of considerable interest. In this article, we discuss the properties
4 C1 G, ~+ e. V+ ?* B; y' V2 Y! N4 Tof cancer stem cells, outline initial therapeutic strategies against them, and present
9 \& I( J' {! ]challenges for the future.: A8 o; g9 I( w/ Z; B$ b" q
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efool

不错，很有价值

Fischer3

好东西，要顶！

ahmusht

have a look

Chris

like it " V9 `! O" l0 X2 U  R
thanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good