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2012年11月 Nature Medicine/ d8 o# I; @2 U8 g# g
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In this issue, Andrew Weng and his colleagues uncover a new " M/ N" v1 M5 c1 ?' W% X
mechanism by which oncogenes regulate leukemia stem cells. Notch-driven
" m- [) O: p- Jinactivation of PKCθ attenuates the accumulation of
% B$ H! r5 `9 v. Ereactive oxygen species to lower oxidative stress in the stem cell population of 7 b4 l0 n% F1 }& \1 L7 G
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The
# O; x+ m& q& g2 P l' qimage shows an electron micrograph of erythrocytes and lymphocytes from a ) O8 m0 ?7 \7 U- \& T
patient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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. i! j3 {& w# N% o2 p7 I# N[hide][/hide] |
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发表于 2012-11-10 12:55
