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求助文献;
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4 P+ F5 k5 v! a a* @+ R% {# e1. The epigenetic landscape of T cell exhaustion.
3 w5 i" B6 F* u: j @https://www.ncbi.nlm.nih.gov/pubmed/27789799/5 R+ g h) S1 W. D1 H1 i3 q
: F0 ^. Q' D0 T* o h6 S' J2. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade: o/ s7 E9 K4 f o
http://science.sciencemag.org/content/early/2016/10/26/science.aaf2807
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2 k8 D' v! a6 g- U0 J- T3. Can T cells be too exhausted to fight back?
8 F' _( X# q: k* A& E; Bhttp://science.sciencemag.org/content/354/6316/1104
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