求一本书:25 years of p53 research

iseeyou1210

最近迷上p53了，想找这一本书来看看。
" p% e! i6 \$ ~* I; Z' @不知道哪位大侠有？
: k  r* `" Q6 l- h书的链接在次！
4 Q% T  L6 G6 U# c, k* E1 Hhttp://www.springer.com/biomed/cancer/book/978-1-4020-2920-2" N- J; l' ?/ c7 p" T/ \$ K! K; f

8 K! `: ]" J7 O" G$ q. i7 l谢谢！

have-a-rest

好书，等着一起分享。3 B0 m3 f/ b. n" b" i, P& o
手头有一篇p53近30年的研究进展小综述，愿与大家一起阅读。' v. Q) ?( A0 i

bobo

http://www.stemcell8.cn/thread-15202-1-1.html6 x  T/ q5 r+ `( _9 Q6 Q3 n

# M& `' q4 [3 f0 U( v上传到电子书专区了

have-a-rest

回顾p53的发现和认识史，作者感慨：When a group believes something, evidence to the contrary tends to be more readily dismissed.0 ?! m& f2 }6 v  v  R8 m1 ~& q9 |
我们目前从事的热门学科是否也存在这种问题呢！

iseeyou1210

谢谢！

张也行

呐也是 谢谢哈

have-a-rest

30 years and a long way into p53 research1 G- h8 _" l4 X! \* S1 {' M, }3 I; l
Pierre Hainaut, Klas G Wiman0 P5 i! Y+ t. P" f0 m8 m
Among the 278 092 publications indexed into PubMed in 1979, a handful of articles stand out as the foundation of one( Z$ ]5 F$ @5 r/ f
of the most profound forays into the molecular basis of carcinogenesis: the discovery of the p53 tumour-suppressor
5 L6 G3 v3 H" |/ R5 nprotein. In the 30 years since then, understanding of p53 has progressed from obscure oncogene to key
2 D, }; h  b3 f, P7 ]/ j) i( Etumour-suppressor gene with clinical potential. Yet, p53 research has not followed a straight course. In this Historical% |# F% [2 l, n1 }* Q) ~: o$ Q
Review, we describe how the 1979 discovery has shaped our view of the molecular basis of cancer, and identify some
# L8 Y5 p4 L$ j  Y7 _! L% Ocrucial steps ahead to transfer the wealth of knowledge accumulated on p53 into applications to cancer prevention, \$ ]1 e8 N# X, h( x( v3 U) l
and treatment.' r! q- t. H1 x& T

franklinhg

不简单的 谢谢