求一本书:25 years of p53 research

iseeyou1210

最近迷上p53了，想找这一本书来看看。
- D2 e! K- M5 l; C( U. Q0 |不知道哪位大侠有？* }  x9 J& x1 V# n* j! e* {* ?/ H3 e
书的链接在次！
1 f/ z  y" q" C! Q& k0 ehttp://www.springer.com/biomed/cancer/book/978-1-4020-2920-2
+ \) Z" w2 w4 x% }
7 R: c# p$ _6 y1 y- W" X0 Z谢谢！

have-a-rest

好书，等着一起分享。
  }# v, A# |( i( U" m1 K: ~  F手头有一篇p53近30年的研究进展小综述，愿与大家一起阅读。
+ s! c! Q+ C1 b

bobo

http://www.stemcell8.cn/thread-15202-1-1.html% m: F; S5 w' }( i! V0 V, U
) S: b: e7 G! D% i' y, n
上传到电子书专区了

have-a-rest

回顾p53的发现和认识史，作者感慨：When a group believes something, evidence to the contrary tends to be more readily dismissed.9 e4 y7 u) `! C4 w
我们目前从事的热门学科是否也存在这种问题呢！

iseeyou1210

谢谢！

张也行

呐也是 谢谢哈

have-a-rest

30 years and a long way into p53 research
; H; N" U0 U) i! g* _' kPierre Hainaut, Klas G Wiman
6 I1 a8 i6 G0 Q: _3 X* |4 HAmong the 278 092 publications indexed into PubMed in 1979, a handful of articles stand out as the foundation of one
. ^& F5 Z5 C  t, a4 D, z  Pof the most profound forays into the molecular basis of carcinogenesis: the discovery of the p53 tumour-suppressor
+ A% P6 W7 l7 i/ d  Bprotein. In the 30 years since then, understanding of p53 has progressed from obscure oncogene to key* ]) t! G7 N1 Z; L$ w* h' k# ?
tumour-suppressor gene with clinical potential. Yet, p53 research has not followed a straight course. In this Historical4 S2 ~$ U/ P8 ~, n! q/ x8 B
Review, we describe how the 1979 discovery has shaped our view of the molecular basis of cancer, and identify some, {# |- ]0 Y! Z7 l7 C
crucial steps ahead to transfer the wealth of knowledge accumulated on p53 into applications to cancer prevention: c% R: l( R" e& i3 u# C! E% i
and treatment.! J5 U) e7 \  W( I

franklinhg

不简单的 谢谢