The stem-cell niche as an entity of action

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Stem-cell populations are established in ‘niches’ — specific anatomic locations that regulate how they1 n9 D: M& l2 X
participate in tissue generation, maintenance and repair. The niche saves stem cells from depletion,6 I6 v( C9 T+ t2 H7 \
while protecting the host from over-exuberant stem-cell proliferation. It constitutes a basic unit of tissue' l( ?7 i, V4 v
physiology, integrating signals that mediate the balanced response of stem cells to the needs of organisms.
2 s8 s  z  p2 gYet the niche may also induce pathologies by imposing aberrant function on stem cells or other targets. The6 H/ n; I. W! i  ~* U
interplay between stem cells and their niche creates the dynamic system necessary for sustaining tissues, and5 j* ~. j" b8 `/ e* L7 y7 _
for the ultimate design of stem-cell therapeutics.

张也行

十分感谢  楼主最近好慷慨啊

张也行

十分感谢  楼主最近好慷慨啊

changylin

感谢

ywna917

十分感谢啊！