《细胞》[Cell]13年3月28日出版pdf全文

nero1981

8 o# ]$ p9 V$ z1 `6 L

, _2 O, b9 w3 y
( l/ j1 T! @% g; @Volume 153, Issue 1; y% h/ B' ?& j+ V# R+ t+ N& n
On the cover: The kind of food an organism consumes has a broad reaching
7 `3 n. J8 |8 ^+ r' Oimpact on its development, behavior, and lifespan. In this issue, two 2 ~6 H/ A7 e0 p3 P$ w
papers, MacNeil et al. (pp. 240–252) and Watson et al. (pp. 253–266), explore
- U( A/ N, q" m( t4 N; Hthe effects of diet on these life-history traits in the nematode C. ! o& j8 e  \  F1 m" f: f
elegans. Combining nutrigenomics and network analyses, they find that ! [# i* d, ?3 ]$ d
different diets affect traits via distinct mechanisms. The response to diet is & N( {- B9 ~6 p  G0 z2 P: d+ l
coupled to metabolic changes, and disruptions of some of these specific 3 e5 k7 Q4 V8 w6 @
metabolic pathways correspond to inborn errors of metabolism in humans. The
9 C* R+ Q/ X  U  A/ _1 G$ ucover features a “native-art-inspired abstraction” of a worm eating a bacterial " r' Y$ N, R( |. T) i: E$ h$ z. Z
diet and illustrates the interconnectedness between diet, nuclear gene # [- o! S, r* `) I% D
regulatory networks, mitochondrial networks, and their effects on life-history
* X7 v' w9 w$ D/ N- |traits such as development and brood size. Cover art by Lesley T. MacNeil.
9 u3 V4 y. ?6 V- Z7 Q
0 ]+ ~: S+ o0 i! I) L0 }1 j

游客，如果你要查看本帖隐藏内容请回复

exin11

sfk06

看看

redmoon610

这个要大大的支持

327670562

试试

ccnuld

学习一下

懵懂干细胞

感谢元老分享

617507911

学习

狼小姐杏

xiongjiedeng

好东西