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本帖最后由 aspen 于 2009-8-31 09:53 编辑
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Anthony DeFranco
. n! \- m1 Q0 H) W/ d' \) R* n/ dDepartment of Microbiology & Immunology, University of California at San Francisco; Y4 g+ m# l' r+ T
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Themes include:3 ? Q5 x2 k! Q; b. }
1. Checkpoints in B cell development: feedback from Ig gene rearrangements
& ]! b4 A8 V$ w# P/ l2. Stromal environment/growth factors for B cell development
) N1 C- Y& S5 J3. Lineage commitment: transcription factors and Notch signaling
& @8 K& p X) D9 G: ~8 Y4. Central tolerance of B cells
& c& M0 E! R7 @3 `; i0 |& y. A5 w5. Peripheral tolerance of B cells
0 m, f7 R4 H% x4 B+ T, ~6. 3 different types of mature B cells: choice of cell fate and relative roles |
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