[全文]丁盛Nat Methods新文章－－提高iPS诱导效率200倍

芷瞻

Nat Methods. 2009 Oct 18.【Epub ahead of print】2 R6 D+ F% F, S1 c& H' {! P

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A chemical platform for improved induction of human iPSCs., r( T5 Z5 p  F8 ~" v! ]- c3 s) l
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Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S.4 ]9 m7 `0 F$ X& a# r! k
Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA., E7 `# ?* K: k

9 \: N- O3 Z+ B( eThe slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, nonviral methods for reprogramming human somatic cells./ U* G* j0 H9 i' k& ~' ]
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PMID: 1983816
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jianlindunev

学习中，感谢

好玩301

怎么下载不了了？仍然感谢

sunyucheng

ddddddd

应菜

能下，谢谢

lorey

顶！好文章

dengyanfei

非常感谢

carolshf

非常感谢

风源

感谢

mmssyyee

请问你有没有这篇文章的methods呀？我在网上下载不了，有的话能不能给我一份啊，谢谢！！！