[全文]丁盛Nat Methods新文章－－提高iPS诱导效率200倍

芷瞻

Nat Methods. 2009 Oct 18.【Epub ahead of print】  y7 \: ?3 f( x

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7 g" ]: M  F5 z+ iA chemical platform for improved induction of human iPSCs.) E) z' @6 t# [

0 i8 A- Y- j% K- G7 ]; SLin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S.3 F$ V  C) L7 H! p! l" y
Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA.7 S' _+ P! }) M
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The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, nonviral methods for reprogramming human somatic cells.* _1 F+ b& Y3 I( q
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PMID: 19838161 R6 C6 h! r" T

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jianlindunev

学习中，感谢

好玩301

怎么下载不了了？仍然感谢

sunyucheng

ddddddd

应菜

能下，谢谢

lorey

顶！好文章

dengyanfei

非常感谢

carolshf

非常感谢

风源

感谢

mmssyyee

请问你有没有这篇文章的methods呀？我在网上下载不了，有的话能不能给我一份啊，谢谢！！！