PDF电子书：Biotechnology 5edition

lifescience1

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2 b7 l" b; q0 M* {Biotechnology
* k, F- K$ T4 N0 n, zFifth edition
6 G) L8 _: h1 s& K) y; z: c+ ~Biotechnology is the major technology of the twenty-first century – yet few1 c( ^/ J7 n. h8 y" [
people realise how much it impacts on many aspects of human society.
, c- I, [% @8 _! vThe defining aim of this new fifth edition is to re-establish the correct
: m+ b4 _! @. w, Sunderstanding of the term biotechnology. Using the straightforward style8 {( ], B% ~1 e) z' p% \
that made the previous editions of his textbook so popular, John Smith
4 w" c7 x, s( }9 Donce again helps students and general readers alike with the deciphering9 j+ p* e6 F0 S2 s5 N3 f5 s
and use of biological knowledge.He explains the historical developments in! H" O, ^. s6 g( V/ E
biotechnology and the range of activities from brewing beer, the treatment
3 t0 K# g5 P% `% ^3 B$ T3 |of sewage and other wastes, and the creation of biofuels. He also discusses$ _( m6 |) R- X& D- F' B
the innovations in molecular biology, genomics and proteomics, systems
0 ]9 K1 X' S$ Cbiology and their impact on new biotechnology. In this edition John Smith5 [: q( \" t6 f: K
also re-examines the ethics and morality of aspects of biotechnology and
- ]( ]# K, N1 W$ ?3 o. v8 n4 q6 `puts new emphasis on stem cells and regenerative medicine and micro2 f( \% U* y8 s' p) F0 ^: Q7 m/ Y
RNA.
3 n2 @+ F7 q* w) D( ]John E. Smith is Emeritus Professor of Applied Microbiology in the
+ L& O3 K3 z/ z8 p8 nInstitute of Pharmacy and Biomedical Sciences, University of Strathclyde,2 M, f% j" r6 U- b0 O" `
Glasgow and Scientific Advisor to GlycaNova, Norway.
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+ v6 C# ~0 F& @' B2 n& Z# @% vPreface
/ U9 Q& D  s- ?1 D8 J' RA defining aim of this fifth edition of Biotechnology has been to re-establish
# D! B  k3 X9 P+ E6 O/ y& tthe correct understanding of the true meaning of biotechnology.
* E/ X3 R! Y! h* N5 N% VBiotechnology is in essence the deciphering and use of biological knowledge., l. o, W1 z& E6 e& a
It is highly multidisciplinary since it has its foundations in many- N  g, \; S5 q( z& r' j2 W2 ?
disciplines including biology, microbiology, biochemistry, molecular biology,; u1 C) G9 j3 n1 o' E% e+ W
genetics, chemistry and chemical and process engineering. It may also
) }9 Y6 K% B1 [, C7 S" fbe viewed as a series of enabling technologies that involve the practical5 S+ s# Q, s7 V% L' m
application of organisms (especially microorganisms) or their cellular components/ b1 z' e6 `. W/ c( |( {2 C* `9 j6 a
to manufacturing and service industries and environmental management.0 Q- _1 S: Z3 U' `: I' T
Historically, biotechnology was an artisanal skill rather than a
' |1 x( j( {- U  rscience, exemplified in themanufacture ofwines, beers, cheeses, etc.where
! P2 y1 J7 {  }# ?; ]) C2 K2 Wthe techniques of manufacture were well worked out and reproducible,
( N1 P( c2 M: O1 b; E& ~) ?# Cwhile the biological mechanisms were not understood. As the scientific* d% L; U- |0 m) R0 u* U; M- j" L
basis of these biotechnology processes has developed this has led to more
, Q( \3 n6 {3 a$ K( _' D* V2 Befficient manufacturing of the traditional processes that still represent the2 a9 S; ^* `% ~
major financial returns of biotechnology, i.e. bread, beers, wines, cheeses,
' D: `/ P; s+ x; J" @etc. Modern biotechnological processes have generated a wide range of new
9 o3 y5 T" V! V; X8 `. J( G/ Pand novel products including antibiotics, vaccines and monoclonal antibodies,4 G/ @, y# f( S
the production of which has been optimised by improved fermentation" `# P) H& O! r: m% {
practices. Biotechnology has been further revolutionised by a range
6 A3 y+ [* G4 v5 q, Jof new molecular biology innovations, allowing unprecedented molecular
' g3 j; O6 z; t: v! xchanges to be made to living organisms. The increasing understanding of
9 M4 O, e6 j# S/ \5 {1 Bgenomics and proteomics has led to the creation of a vast range of transgenic/ R* X* B2 n/ H' L9 B2 v9 ^
microorganisms, agricultural (genetically modified) crops and animals,
; `7 r, o9 V1 iand major new recombinant protein drugs, and has revolutionised- `* N9 y  N- p% W! I+ g
activities in the traditional food and drinks industries. In the environment,, S3 q, s, G" b/ i
biotechnology innovations are creating major advances in water
0 t; c4 N4 F3 Z/ }. j' _and land management and also remediating the pollution generated by3 L0 R7 {' C4 a  ]
over-industrialisation.
& a# D' Y' E" }" jThere have been vast investments in molecular diagnostics, not only in
& v- G/ i) O; M( H% Kmedicine but in plant and animal agriculture and the environment. Will7 T  ~- d, ^9 O: E$ b5 z1 T
the huge potential of stem cells for remedial medicine soon be realised?1 K0 A5 d. G2 ^/ _
Until recently, much attention has been given to determining the ‘nuts3 G/ D5 G' ^/ ~$ V, Q: L
and bolts’ of biological systems. Now, systems biology is aiming to describe) X* R- |- W- ^- O; w( r. ?% D
and to understand the operation of complex biological systems and ultimately
) I, B  F1 \7 M1 ]to develop predictive models of, for example, human disease and& ~: z, b- V+ e4 A9 v; M3 J1 m- U& [
complex fermenter systems used in biotechnology.9 H. M& ~5 J* F! V) }. B/ J$ |
Some of the new aspects of biotechnology, such as genetic engineering,
( K+ {8 Y) r& M) j( L. Thave aroused certain social sensitivities of an ethical, moral and political  @; ^# z% I2 X: ?" F1 ~
character. Regulatory authorities throughout the world are now examining- }6 t; U% q2 U$ ^$ G0 J1 Z; I; S
the implications of these new and revolutionary techniques. It is hoped that2 ]% e! M8 t1 u) A) }& b
common sense will prevail.
( `3 H2 M! W7 S2 H: ]Undoubtedly, modern biotechnology can only maximise its full potential1 z# Z' C9 A2 r. Q7 M9 \& s
to benefit mankind through achieving a basis of public understanding,& M* Q2 ]' {4 l+ u+ d. g7 o% D. q7 f
awareness, and knowledge of the technologies. Participating scientists must learn to communicate openly with the public and attempt to demystify the0 z) V  O$ _" n+ a" Z9 W, Y9 r
complex nature of living systems. By doing so they will generate a greater
3 x( z- f9 j* v3 flevel of confidence and trust between the scientific community and the
3 `+ [5 u, n) @# m' hpublic at large.
0 u+ i$ u! @* y1 n- e/ y) HThis expanded fifth edition of Biotechnology is again aimed to give an: y, l' I+ x# d0 L
integrated overview of its complex, multifaceted and often ill-maligned
% x4 q) V: K2 X! u: e( Q3 ?subjects, and for some young readers to point the way forward to exciting,
! P# Z8 T$ w% B& p9 Ssatisfying and rewarding careers. Biotechnology will undoubtedly be the
: P) p) X+ Z. f6 r. @2 [" n* amajor technology of the twenty-first century and should be so recognised8 b4 F* J- k2 `+ u, G' z7 c
by the lay public.+ X) P- G1 j. ]- ~- c# W: |
I amagain deeply indebted to the long-suffering Elizabeth Clements for
/ B2 M& V6 W* i# w8 ?* k! m/ W! Kher skilful processing of the manuscript and her continued dedication.

细胞海洋

修改了一下 ，既然下载收费 浏览帖子就不要收费了 重复了
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请见谅

lifescience1

: g# A+ U. j& j4 n6 H& N1 A

$ t- }) v9 C6 I8 t; z回复 2# 细胞海洋
+ A( C$ |. l4 E; \) L没关系。版主是对的。我是第一次发。不清楚O(∩_∩)O哈！。谢谢！
8 [: L- k5 F2 u* e1 m( R. x很抱歉给你添麻烦了。

hualin840518

这本书论坛有5 V; [$ p& k( Z% Q( a8 g4 A9 B
我很早就发过
8 g* L4 o2 y& D3 p7 c呵呵3 P) D1 _5 _9 p" g0 s
辛苦了

张也行

恩 这本书以前有人发过。不过还是辛苦楼主了 谢谢

pada-44

谢谢

lchanlon

看看！

awen

爷爷都是从孙子走过来的。  

dypnr

偶啥时才能熬出头啊.  

泡泡鱼

厉害！强~~~~没的说了！