PDF电子书：Biotechnology 5edition

lifescience1

# ~$ r# |4 S. n9 r! w" d& b
- R) W9 A8 L! B( q* L4 V$ f. rBiotechnology% `% u! L  m: Q7 R5 U1 U' [
Fifth edition0 b5 i) Y! |; i7 Q3 q: B, b0 ?
Biotechnology is the major technology of the twenty-first century – yet few
; V' H$ Z( e3 dpeople realise how much it impacts on many aspects of human society.1 T  j5 K$ B+ W6 z
The defining aim of this new fifth edition is to re-establish the correct
: i! A! ?4 a2 |0 W+ t5 |understanding of the term biotechnology. Using the straightforward style
2 ^* n; y2 H& X: hthat made the previous editions of his textbook so popular, John Smith
$ a: Z+ U# e# ^- z! K2 h* N3 zonce again helps students and general readers alike with the deciphering: ]4 d" T5 ?- C$ Q" C& ^2 }
and use of biological knowledge.He explains the historical developments in' I* V" j2 i. y# z3 S9 W
biotechnology and the range of activities from brewing beer, the treatment, C: _  T" a: a! L* d; |  o' B
of sewage and other wastes, and the creation of biofuels. He also discusses' ~2 F* Z: b- o" q. z5 @
the innovations in molecular biology, genomics and proteomics, systems2 l) ^+ F! }% r
biology and their impact on new biotechnology. In this edition John Smith) o  M4 z! C% [/ c2 U7 k
also re-examines the ethics and morality of aspects of biotechnology and
6 ~! B( P5 D/ S! V  q& s3 i, u- }) lputs new emphasis on stem cells and regenerative medicine and micro; g: M* B$ n+ u: A& [4 S' w
RNA.' `" ]/ ~& x% a/ I8 j$ [$ H1 j
John E. Smith is Emeritus Professor of Applied Microbiology in the0 N- ?- B% E, ?' T0 A5 W9 ~
Institute of Pharmacy and Biomedical Sciences, University of Strathclyde,) @. x1 ~- p- j# V/ B# O( s
Glasgow and Scientific Advisor to GlycaNova, Norway.1 w: |' I9 e$ `* _# A2 O  @

* y6 g! W! }( B7 |: _4 b$ `Preface
1 b; m4 l2 H& r- |4 ?! a' iA defining aim of this fifth edition of Biotechnology has been to re-establish$ {6 s5 L# ?$ S6 y- o
the correct understanding of the true meaning of biotechnology.- \/ @0 ?. D$ }# `; T5 t
Biotechnology is in essence the deciphering and use of biological knowledge.( k5 K1 ~8 [0 R% x/ P
It is highly multidisciplinary since it has its foundations in many
2 S1 J6 L5 C# I& P0 f6 Cdisciplines including biology, microbiology, biochemistry, molecular biology,
% |, M( o6 d" i' g. Pgenetics, chemistry and chemical and process engineering. It may also
$ H% t4 b8 N8 Rbe viewed as a series of enabling technologies that involve the practical
& B7 C+ B' Q) lapplication of organisms (especially microorganisms) or their cellular components. D( o! [; v9 X  @0 K: P  ~
to manufacturing and service industries and environmental management.
: c6 E6 A9 F; Q$ ]$ YHistorically, biotechnology was an artisanal skill rather than a
3 I* k! i  P9 A: u) ~science, exemplified in themanufacture ofwines, beers, cheeses, etc.where
8 S6 @9 y7 R0 K" p7 w& kthe techniques of manufacture were well worked out and reproducible,) U' N7 C) y% \* P8 a) L( C
while the biological mechanisms were not understood. As the scientific5 R3 x) z' J0 `- {; h- v
basis of these biotechnology processes has developed this has led to more' L. E( R* o) S$ Q% v4 m$ a
efficient manufacturing of the traditional processes that still represent the
& N2 }) ?; x: T. K( Y# }major financial returns of biotechnology, i.e. bread, beers, wines, cheeses,4 u# }/ j4 y6 Y' j0 e7 K
etc. Modern biotechnological processes have generated a wide range of new
) g4 v7 D& h/ I& `1 s& wand novel products including antibiotics, vaccines and monoclonal antibodies," Y  m4 s- V! i+ D2 V: h
the production of which has been optimised by improved fermentation8 T8 p, s5 Y0 L* W8 M' K
practices. Biotechnology has been further revolutionised by a range( H3 S! K1 d* o
of new molecular biology innovations, allowing unprecedented molecular% E$ Q( i  \* K. l4 V+ \
changes to be made to living organisms. The increasing understanding of
* q2 P- i" J  r$ q# m$ xgenomics and proteomics has led to the creation of a vast range of transgenic& ^, {7 t4 t1 @5 w$ K% ^
microorganisms, agricultural (genetically modified) crops and animals,4 y  `, U0 m5 Q, f3 Y; |/ T
and major new recombinant protein drugs, and has revolutionised
" N7 p5 I, z8 @! Z, Uactivities in the traditional food and drinks industries. In the environment,
2 C, a! y4 I, J# ]  V( Lbiotechnology innovations are creating major advances in water7 Q) C* _% K. G* v% g
and land management and also remediating the pollution generated by
9 U% ]8 ^' J9 Pover-industrialisation.
' e8 C+ V( y8 {! Z6 ?There have been vast investments in molecular diagnostics, not only in3 e) @- M" U( z- d
medicine but in plant and animal agriculture and the environment. Will
+ b# U: k& t# O6 Z' _, k* pthe huge potential of stem cells for remedial medicine soon be realised?
. Y. q4 ]! y: W% \" i2 H; SUntil recently, much attention has been given to determining the ‘nuts" J" E4 q* _9 C) t0 W" t6 N
and bolts’ of biological systems. Now, systems biology is aiming to describe
% ~" `6 l; X; j  J/ ^+ n5 D0 Wand to understand the operation of complex biological systems and ultimately
. V( N8 q5 f6 \! T5 Dto develop predictive models of, for example, human disease and7 Y9 Y1 z1 e2 r- S: T9 y
complex fermenter systems used in biotechnology.
  P3 p) d% G% B3 r+ z. n/ NSome of the new aspects of biotechnology, such as genetic engineering,
) `/ d: B6 P) ?! j# q7 }have aroused certain social sensitivities of an ethical, moral and political, B7 g" V5 P8 N; O* y
character. Regulatory authorities throughout the world are now examining
. J5 ]  ~$ h& v* f' w* kthe implications of these new and revolutionary techniques. It is hoped that# D6 }- Z; Z( D- I6 W/ S  i" T
common sense will prevail.) B; x+ v7 _) I  l# R
Undoubtedly, modern biotechnology can only maximise its full potential) x1 J4 q& E8 v; W5 S. A2 ~
to benefit mankind through achieving a basis of public understanding,
  \/ ?) `. D- p/ _awareness, and knowledge of the technologies. Participating scientists must learn to communicate openly with the public and attempt to demystify the
3 ^2 S; }* `4 m; m5 Bcomplex nature of living systems. By doing so they will generate a greater2 ?1 l1 n7 L$ h! a
level of confidence and trust between the scientific community and the3 ]3 R" z0 Z+ I3 ^
public at large.7 P  D+ t# P% W3 Y4 E
This expanded fifth edition of Biotechnology is again aimed to give an
0 P- C) V7 W6 R5 e6 aintegrated overview of its complex, multifaceted and often ill-maligned
  z/ D+ i8 ^" X. g( [/ vsubjects, and for some young readers to point the way forward to exciting,; H0 Y1 W- A+ Y& y4 C
satisfying and rewarding careers. Biotechnology will undoubtedly be the
: s; o/ F/ L3 o0 F5 N' s4 b8 Cmajor technology of the twenty-first century and should be so recognised. W1 T* K/ N0 A* t# j" v
by the lay public.0 |& C8 T* T: e9 O8 `
I amagain deeply indebted to the long-suffering Elizabeth Clements for2 W3 S" L% ]) x4 X+ b5 G2 x
her skilful processing of the manuscript and her continued dedication.

细胞海洋

修改了一下 ，既然下载收费 浏览帖子就不要收费了 重复了
, |% t- v7 `" a& ~  @! e0 a* p. `( v1 n# B) h! h: {
请见谅

lifescience1

, e4 |2 D" n9 W7 b  C6 U! z5 T. i! H+ l1 R
回复 2# 细胞海洋   ~4 t  ]7 x% L; j
没关系。版主是对的。我是第一次发。不清楚O(∩_∩)O哈！。谢谢！ 3 h% r. a8 j+ L- `7 H
很抱歉给你添麻烦了。

hualin840518

这本书论坛有
7 ~2 J% c: y( G3 m我很早就发过  ^  j2 _' X* V) B2 s+ S
呵呵" Z! M6 n  U2 H. z6 p$ C* o
辛苦了

张也行

恩 这本书以前有人发过。不过还是辛苦楼主了 谢谢

pada-44

谢谢

lchanlon

看看！

awen

爷爷都是从孙子走过来的。  

dypnr

偶啥时才能熬出头啊.  

泡泡鱼

厉害！强~~~~没的说了！