PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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. b' F! d# E5 {FOREWORD
8 {: d% k8 b  H$ ~Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.
2 P5 V+ R+ U6 X2 f% F) y  d+ yMaking this potential a reality requires an international effort. The recognition6 w3 u3 v* Q& E
that such a promising yet multifaceted discipline needs fostering led to the establishment
) c; B% f/ }6 ~of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
  m" u1 Q. W& i2 h  B8 G6 |; z3 `ISSCR is the development of tools to ensure the success of stem cell researchers. What
/ L) h7 l0 J) d# _, ~better way to do this than to collaborate with Current Protocols to develop this valuable
8 f2 B: u( O: @% G+ [1 Kcompendium of protocols in stem cell biology?
9 i% x! A% M: T2 b) n, QStem cell researchers have developed a number of breakthrough techniques, from the& B9 A0 }; `+ T9 w, a3 L
derivation and manipulation of pluripotent embryonic stem cells to purification and
/ K$ v" q3 ?2 o7 E* ytransplantation of tissue-restricted stem cells from adult organs. A number of laboratories
1 x2 `% s+ r* A1 j& R% j; ~have become leaders in the field as a result of developing such techniques. The more! L# M! o8 t/ [5 Y
efficient scientists are at implementing new and powerful methodologies in their own9 J5 ^+ l2 P( Y" |1 B( U0 v
laboratories, the faster stem cell biology will advance our understanding of normal
2 P/ l, k0 _2 W9 j' l$ t& P  p) Ydevelopment and lead to the development of therapies. Thus, the availability of quality' `0 \3 r' {. A+ o8 ~/ y
protocols will have amajor impact on the success of the entire field. Current Protocols has
; Y" _) ^8 H; z1 `long been the premier volume for proven in-depth protocols regarding many aspects of6 k7 Y; z, n0 d% q6 g
biology, and this volume on stem cell biology will prove a valuable addition to researchers
" V" f( s  M( V2 o5 W2 n" ~worldwide.
  p$ G$ j, G5 g2 @Experiments in stem cell biology must be interpreted with great caution as well as
2 v8 ?. Y1 s' H5 X9 qopenness to alternative explanations. For example, the recently discovered phenomenon  z$ [5 z) r9 \# [+ ]$ M2 Y
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral
% O+ S9 M1 \6 g+ f; a+ ltissues were initially misinterpreted as evidence for stem cell trans-differentiation.
" H; ~8 c; J- m' k# \4 Y* c- jIt is very important that this compendium of protocols highlight potential pitfalls as well, Z8 j, h) L/ z7 d
as maintain the opportunity for clarification and correction when the need arises. The; k" F  X% D9 N3 ^7 p$ f& d
fact that these protocols will be provided online will help ensure that researchers always4 |0 N3 v* g! f9 `' R
have the latest, most up-to-date protocols available to them.+ o- N7 k: t( N5 A0 w
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine% O% b2 |, O/ u: o- I4 G
push to share information and interact so that the field can move forward quickly. There
- K, Z. B: j6 P1 V2 Y) uis a drive to develop not only excellent basic research skills but to bring the findings
2 s- Z9 ~9 e! _$ B  zto clinical use so that patients can benefit. As a Hematology Attending Physician at5 n& m0 U/ T) ?, N
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
4 c5 A, @7 V; Q' t' G. N; o0 U4 ^5 p$ Oand am drawn by the need to translate our research findings into therapies to help treat a' O% N5 Y- a2 m; Z. s
number of diseases. The promise is great, but we need to deliver, and I believe Current
4 l/ Q2 M# Z; J/ x: yProtocols in Stem Cell Biology will help tremendously./ C) R4 E% y7 }
Leonard I. Zon
6 o( S9 m; F# {; FCurrent Protocols in Stem Cell Biology$ o! Y# u( x+ L* c$ F! W& _( F0 G" t
Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).
% z- H( Q. I1 x4 `* `- WDOI: 10.1002/9780470151808.scfores1, W* q. j* X3 |- y# S
Copyright C
2007 John
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  k* a2 p! l, b; ?0 I/ o: w附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了
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