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本帖最后由 细胞海洋 于 2010-6-19 13:37 编辑 ) K9 N1 n5 I% j5 D/ [" h
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FOREWORD! J! H5 e2 W6 A6 r* S4 N- k1 d& `
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.$ n9 r& h1 Y# K5 J4 ~
Making this potential a reality requires an international effort. The recognition
/ f: C+ N ~& p) Uthat such a promising yet multifaceted discipline needs fostering led to the establishment
& L2 O0 g1 z0 P" z2 r2 {of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the! c6 U n3 I; Q. m0 I
ISSCR is the development of tools to ensure the success of stem cell researchers. What
' ], q* p5 @ q! ?9 k5 W- {# Nbetter way to do this than to collaborate with Current Protocols to develop this valuable* f& v5 r# _3 I; p l4 b/ ]
compendium of protocols in stem cell biology?
! P' }! B2 \, H) nStem cell researchers have developed a number of breakthrough techniques, from the
) d: ]4 r, J% U/ L9 b5 ? bderivation and manipulation of pluripotent embryonic stem cells to purification and
5 U, t1 R; a$ C- A: \. o: h9 Otransplantation of tissue-restricted stem cells from adult organs. A number of laboratories; R* `1 s+ ]/ q& I: }9 }' @# S2 z/ K
have become leaders in the field as a result of developing such techniques. The more* D. Q0 Y/ s8 }# v1 t0 f) U* {
efficient scientists are at implementing new and powerful methodologies in their own
1 @# Y0 I: X3 ^5 ^laboratories, the faster stem cell biology will advance our understanding of normal
3 z! v% |1 ]# Wdevelopment and lead to the development of therapies. Thus, the availability of quality! C+ K2 ~" J$ y2 O1 X
protocols will have amajor impact on the success of the entire field. Current Protocols has
( u' Q5 z- g! along been the premier volume for proven in-depth protocols regarding many aspects of# A1 i6 f" G& D0 T2 o
biology, and this volume on stem cell biology will prove a valuable addition to researchers, m5 S0 d+ L5 B# J
worldwide.( A& [0 I5 c3 X. e- ?/ ^6 @/ R
Experiments in stem cell biology must be interpreted with great caution as well as
* j/ A7 X9 K# n9 D- u1 Gopenness to alternative explanations. For example, the recently discovered phenomenon. K2 ~9 u1 @* V* Y, g
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral
5 p/ o8 D9 v# wtissues were initially misinterpreted as evidence for stem cell trans-differentiation.
* _& y" G/ f" a9 N$ u7 N* n; \It is very important that this compendium of protocols highlight potential pitfalls as well6 ~0 m' j2 t% g7 _# V. X
as maintain the opportunity for clarification and correction when the need arises. The
) ? P# ~4 k- y6 Nfact that these protocols will be provided online will help ensure that researchers always, V) C. f( @7 S; b
have the latest, most up-to-date protocols available to them.( S3 D. j, A/ V3 Q
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine
5 u1 O6 |; @1 H. Gpush to share information and interact so that the field can move forward quickly. There
/ f% D$ a, ]1 T: Z) xis a drive to develop not only excellent basic research skills but to bring the findings- s+ C3 A9 ^5 ]: x
to clinical use so that patients can benefit. As a Hematology Attending Physician at
( h/ [# l* Q/ ]" }Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
/ q- ]6 ]8 U+ n a3 Kand am drawn by the need to translate our research findings into therapies to help treat a
+ |/ t9 g/ @/ q, t7 \) r2 mnumber of diseases. The promise is great, but we need to deliver, and I believe Current# i: ] |* V/ _+ M# F' g
Protocols in Stem Cell Biology will help tremendously.% ~- b( {* c8 [" m+ N, k6 t Q
Leonard I. Zon, `3 x5 w" b$ A" x* }! P* n+ `
Current Protocols in Stem Cell Biology! u/ A; j/ _6 M7 ?
Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).
) E+ x1 e g1 T" ]+ @& ^' ~" ZDOI: 10.1002/9780470151808.scfores1
( I- Z5 M. |: O, c2 F& kCopyright C 2007 John$ M9 r9 r/ g7 X* O& \+ n3 @3 B
& s' I6 ]. o9 k# j/ ^* ^附件为pdf全文,感谢原创提供者 ,大家回复之后就可以下载了
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