PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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FOREWORD' z4 v- \% q- p' o* B# _2 k
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.9 w1 e% i. ?* {
Making this potential a reality requires an international effort. The recognition
0 O- _0 B( y, W0 f+ k, l* Qthat such a promising yet multifaceted discipline needs fostering led to the establishment/ M& B+ h6 q$ Q- N5 r
of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
. H2 m* ~) v" M% p# t, EISSCR is the development of tools to ensure the success of stem cell researchers. What
" Y( Z- I7 @5 Rbetter way to do this than to collaborate with Current Protocols to develop this valuable2 n, y0 i- u$ [
compendium of protocols in stem cell biology?; j9 j) Q9 ~' k$ _7 E
Stem cell researchers have developed a number of breakthrough techniques, from the
4 {2 d* |. f9 E% q3 D  U- Fderivation and manipulation of pluripotent embryonic stem cells to purification and
7 o7 Y' Q, s- Etransplantation of tissue-restricted stem cells from adult organs. A number of laboratories/ U# w* b0 `; W! y3 b* |8 p
have become leaders in the field as a result of developing such techniques. The more6 n" }+ m/ S) t1 h3 r' u! s0 N8 M
efficient scientists are at implementing new and powerful methodologies in their own
  h) g' p( m+ E9 Olaboratories, the faster stem cell biology will advance our understanding of normal3 q0 v3 @8 c3 y$ K3 ]
development and lead to the development of therapies. Thus, the availability of quality
4 G, E% |8 n9 w1 f6 X2 R& Tprotocols will have amajor impact on the success of the entire field. Current Protocols has0 x/ d- r6 L7 S3 w1 v$ m
long been the premier volume for proven in-depth protocols regarding many aspects of8 {4 Z( s: P. S' G
biology, and this volume on stem cell biology will prove a valuable addition to researchers1 n& m( C2 _: X) ]
worldwide.
) @3 @) Q" \. Q+ HExperiments in stem cell biology must be interpreted with great caution as well as
, m' Y4 o3 c* b, ?. Sopenness to alternative explanations. For example, the recently discovered phenomenon9 w( c0 I# b% C# t2 R! M$ Y. Y
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral
. Y0 |& x. t6 i% Z$ l7 G+ g& @# [2 [tissues were initially misinterpreted as evidence for stem cell trans-differentiation.4 e, j& ~2 l0 N1 Q0 B
It is very important that this compendium of protocols highlight potential pitfalls as well" \: c1 Y$ o  N- [4 o7 z1 O. a
as maintain the opportunity for clarification and correction when the need arises. The% v! e0 h+ ]5 u8 K2 M1 T; o
fact that these protocols will be provided online will help ensure that researchers always8 j8 M0 A# d7 w. r) l$ Q
have the latest, most up-to-date protocols available to them.6 B1 X: G9 g7 i: X& s9 i
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine# e) }5 Q. ]! r0 z6 f1 r
push to share information and interact so that the field can move forward quickly. There5 f' O9 D" Z$ O# o
is a drive to develop not only excellent basic research skills but to bring the findings8 p" H9 N4 k% ^# d& o
to clinical use so that patients can benefit. As a Hematology Attending Physician at' q+ I2 U. N6 c: ]+ g! f9 X
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia5 N4 Z% [! y0 ]  p6 D& U! o
and am drawn by the need to translate our research findings into therapies to help treat a
' @- o. V. g8 c( D  V7 [1 S1 |number of diseases. The promise is great, but we need to deliver, and I believe Current- R  ~' R* W# x, Y# `! Q
Protocols in Stem Cell Biology will help tremendously.
& ^. ]% g: _7 uLeonard I. Zon
2 a# y' V7 _' A) \- D/ CCurrent Protocols in Stem Cell Biology1 _% ?5 m7 m+ N& ^
Published online June 2007 in Wiley Interscience (www.interscience.wiley.com)." ~" N' ~/ t' H# o) x4 |
DOI: 10.1002/9780470151808.scfores1
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2007 John
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4 ^  \7 x0 P# _, ~& P9 e, p9 ?% X附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了0 |9 Y$ I3 P, ]2 l

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xiaodongqin

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Jonathan

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zpzp0312

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zisu_yu

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王乾

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horst

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dragon513

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