PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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" v) S7 |2 O. ?FOREWORD* c6 V. |6 i% o- e! v# M
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential.
/ K+ p- t( ^$ MMaking this potential a reality requires an international effort. The recognition
8 A$ o9 f7 H$ H, ]that such a promising yet multifaceted discipline needs fostering led to the establishment
& p# c) d- _8 {1 W+ @2 Qof the International Society for Stem Cell Research (ISSCR). Central to the efforts of the9 B2 v6 I# R! [8 ?
ISSCR is the development of tools to ensure the success of stem cell researchers. What4 z! {$ N5 Y5 ^7 `' K
better way to do this than to collaborate with Current Protocols to develop this valuable) I% c5 Z, \; Q! b. f& \
compendium of protocols in stem cell biology?
. Y8 d3 m- U- |! g9 H! pStem cell researchers have developed a number of breakthrough techniques, from the
  W- H" o( [! g/ \* R8 @& `/ Bderivation and manipulation of pluripotent embryonic stem cells to purification and
. l' ]4 b9 |* f; W1 Htransplantation of tissue-restricted stem cells from adult organs. A number of laboratories
" r$ D6 |3 r# T1 h! b' I  ~have become leaders in the field as a result of developing such techniques. The more
" u% O2 Y/ P; Z% \, hefficient scientists are at implementing new and powerful methodologies in their own
# A5 u1 I4 T$ }$ `3 g8 vlaboratories, the faster stem cell biology will advance our understanding of normal$ g. L; X5 L; w; l) f+ e
development and lead to the development of therapies. Thus, the availability of quality8 Y7 N- n3 [( c, h4 g; e: Q9 g
protocols will have amajor impact on the success of the entire field. Current Protocols has
3 L- J: T' X: o/ Along been the premier volume for proven in-depth protocols regarding many aspects of
8 Z+ e0 G0 m8 u" abiology, and this volume on stem cell biology will prove a valuable addition to researchers# v( P1 W5 o( f3 q, c7 c
worldwide.
/ l' \, U$ x: M8 z( d( \Experiments in stem cell biology must be interpreted with great caution as well as
$ }4 g' t4 l* n3 [openness to alternative explanations. For example, the recently discovered phenomenon% m: g8 I1 I% H# a. X' Z7 V/ G, t2 w& i
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral+ l: U. k/ q& e8 l1 s
tissues were initially misinterpreted as evidence for stem cell trans-differentiation.( d9 g5 z, L  }  _# S* N
It is very important that this compendium of protocols highlight potential pitfalls as well
9 x3 D- F0 M) c) {+ M! l! V  ]+ Qas maintain the opportunity for clarification and correction when the need arises. The! U- M* j4 M4 o6 `! s
fact that these protocols will be provided online will help ensure that researchers always9 U; k7 C% |+ J
have the latest, most up-to-date protocols available to them.- S7 K- N9 _& l$ `
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine5 E: G5 y; N! `6 F) C9 i7 f) ]1 t! n/ p
push to share information and interact so that the field can move forward quickly. There) c0 q0 E: q  H9 Z/ F4 s
is a drive to develop not only excellent basic research skills but to bring the findings
6 [/ K( l. |3 ~5 Z1 r4 u% Mto clinical use so that patients can benefit. As a Hematology Attending Physician at
0 M3 k+ v6 A* F; E7 nChildren’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
* ?6 e5 {; N; R9 ]4 Nand am drawn by the need to translate our research findings into therapies to help treat a
; `4 h& l. R! a! u% I- K! E4 M, ]number of diseases. The promise is great, but we need to deliver, and I believe Current
% g) k0 o( F- G& ZProtocols in Stem Cell Biology will help tremendously.4 ?* L+ I  o6 m6 h, E
Leonard I. Zon
; E5 ~8 o: F7 s6 nCurrent Protocols in Stem Cell Biology
1 ?8 E" x* X, ^  I& YPublished online June 2007 in Wiley Interscience (www.interscience.wiley.com).
# z. c3 \8 _. ?; G/ Z9 p/ SDOI: 10.1002/9780470151808.scfores1- |& E: @( |$ X9 _: i! M/ [
Copyright C
2007 John
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/ {5 w. t! F' E1 R) X; S附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了
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