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本帖最后由 细胞海洋 于 2010-6-19 13:37 编辑 5 f, l- `- ]) @& [6 t9 @
' P$ a# W2 U0 ]' G9 @" A& a" IFOREWORD
# }! R' F( a! fStem cell biology is emerging as a field in biology with tremendous therapeutic potential.
4 r8 Y6 I3 ]3 U+ ?% x9 eMaking this potential a reality requires an international effort. The recognition
0 v! W9 o8 l/ g6 a+ D' W+ P0 ]that such a promising yet multifaceted discipline needs fostering led to the establishment/ z! b5 W- I( Z
of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
2 A x% Z; m: ^/ l" U# u4 zISSCR is the development of tools to ensure the success of stem cell researchers. What
. _; i/ q; R# @- ?, i3 Ebetter way to do this than to collaborate with Current Protocols to develop this valuable0 q- N0 d8 C% d: |) S5 m# S
compendium of protocols in stem cell biology?2 F5 a R: t& \
Stem cell researchers have developed a number of breakthrough techniques, from the
+ U5 x; j9 F5 X; P4 aderivation and manipulation of pluripotent embryonic stem cells to purification and% S2 S' [7 n. n
transplantation of tissue-restricted stem cells from adult organs. A number of laboratories: O; y1 X' I: W4 C/ }2 K3 L$ A
have become leaders in the field as a result of developing such techniques. The more, C7 H& t( ^7 {
efficient scientists are at implementing new and powerful methodologies in their own9 ?2 K2 v. r/ b+ O" {( \4 Y9 _) Y
laboratories, the faster stem cell biology will advance our understanding of normal
. ?, _% f) K1 u8 ~7 B# A; P' s3 Vdevelopment and lead to the development of therapies. Thus, the availability of quality
0 @ S9 f3 v: Nprotocols will have amajor impact on the success of the entire field. Current Protocols has; t# d, Y' Q: P$ |& ? [
long been the premier volume for proven in-depth protocols regarding many aspects of2 \6 u2 v, h* @
biology, and this volume on stem cell biology will prove a valuable addition to researchers' C! V7 \; b! F
worldwide.
$ k; ^. S3 T9 a) d; j$ c# e( [) TExperiments in stem cell biology must be interpreted with great caution as well as
4 h) U! s9 i8 z9 X7 ~* U7 Vopenness to alternative explanations. For example, the recently discovered phenomenon/ B2 L5 a. d u
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral0 K) b8 O1 y" F; R! p$ l; k
tissues were initially misinterpreted as evidence for stem cell trans-differentiation.
( o# [' l/ P9 [+ F" D6 CIt is very important that this compendium of protocols highlight potential pitfalls as well
8 f# e* N! o* \* k' O& ras maintain the opportunity for clarification and correction when the need arises. The
6 ^8 W9 R6 I G6 _; _fact that these protocols will be provided online will help ensure that researchers always/ d" o/ P2 y, a% t
have the latest, most up-to-date protocols available to them.# c: @% R) }5 ~1 X$ m
The stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine
+ z8 {! x( C1 b8 Qpush to share information and interact so that the field can move forward quickly. There
0 J8 z+ Y! h; G' X! Lis a drive to develop not only excellent basic research skills but to bring the findings; { k4 o$ a Q0 L9 W1 ?- A
to clinical use so that patients can benefit. As a Hematology Attending Physician at" t {. W* _9 ^" ]
Children’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia
( i2 J5 Z. e" l: @& v5 Zand am drawn by the need to translate our research findings into therapies to help treat a4 }: n" v/ x3 c) a& n
number of diseases. The promise is great, but we need to deliver, and I believe Current
; h+ [- {/ b0 a4 V o# q" RProtocols in Stem Cell Biology will help tremendously.& N2 y( m7 G0 ?
Leonard I. Zon) E' t2 a/ I0 u9 Z$ ^
Current Protocols in Stem Cell Biology$ @4 Y8 Y; ]; `, P6 }' e! P2 a0 P
Published online June 2007 in Wiley Interscience (www.interscience.wiley.com).
- c' ?6 _8 P& q5 |; UDOI: 10.1002/9780470151808.scfores1
i+ e% Q* z f8 {Copyright C 2007 John
F8 `. {2 z! O! Q2 P6 h3 j2 X8 \- J! E
% ~# E q E N3 Y% N附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了
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