PDF电子书：Current_Protocols_in_Stem_Cell_Biology

guokeyi

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+ U6 }5 {% h" a9 c$ i4 c1 \FOREWORD# @6 y2 B3 ]: S0 `2 v: K3 o6 _8 R% [
Stem cell biology is emerging as a field in biology with tremendous therapeutic potential./ U- O4 ?+ a$ }0 K$ Y
Making this potential a reality requires an international effort. The recognition5 z+ E+ S* b/ y) f2 ^, L5 Y
that such a promising yet multifaceted discipline needs fostering led to the establishment) M$ m1 e8 }3 n
of the International Society for Stem Cell Research (ISSCR). Central to the efforts of the
1 a3 ]! W2 ~' X$ uISSCR is the development of tools to ensure the success of stem cell researchers. What
! ~2 L* O% T7 K" F2 Y8 lbetter way to do this than to collaborate with Current Protocols to develop this valuable
% l' M  M# x9 F2 Ycompendium of protocols in stem cell biology?
! x( p0 A( ]9 a0 @/ ?Stem cell researchers have developed a number of breakthrough techniques, from the0 v1 j( P; \! |6 v# K1 k
derivation and manipulation of pluripotent embryonic stem cells to purification and
0 l; v* i4 V' d5 a+ Z5 `transplantation of tissue-restricted stem cells from adult organs. A number of laboratories8 v" x4 d* Z1 }; L+ L
have become leaders in the field as a result of developing such techniques. The more
/ F9 U$ |' f0 ^3 {efficient scientists are at implementing new and powerful methodologies in their own
  }# c1 I4 N: n% e+ m0 \1 {laboratories, the faster stem cell biology will advance our understanding of normal6 U8 X8 W- W4 s% K
development and lead to the development of therapies. Thus, the availability of quality
* B7 W" R/ Z* [- Y3 s& F& Cprotocols will have amajor impact on the success of the entire field. Current Protocols has  z5 L& r* t3 g4 |. e8 ^( {# W
long been the premier volume for proven in-depth protocols regarding many aspects of
1 W- h; R  K3 D0 @biology, and this volume on stem cell biology will prove a valuable addition to researchers
" n0 A9 v+ O( kworldwide.5 t2 n, Q6 v8 E: x7 y" v- @, V
Experiments in stem cell biology must be interpreted with great caution as well as
$ |( t/ B! f1 mopenness to alternative explanations. For example, the recently discovered phenomenon' S& x: D. E: d' ~0 z* n* D
of cell fusion in vivo or the existence of tissue-restricted blood stem cells in peripheral
9 X* u& T5 q) f- b3 ]: \tissues were initially misinterpreted as evidence for stem cell trans-differentiation.7 Z/ d0 u5 F6 S0 V
It is very important that this compendium of protocols highlight potential pitfalls as well4 l. n9 o+ A" |
as maintain the opportunity for clarification and correction when the need arises. The
# W; U, ]4 l2 R, @( K- c9 O5 Jfact that these protocols will be provided online will help ensure that researchers always) T6 C+ q5 P: p2 D/ d4 O6 v1 R: c
have the latest, most up-to-date protocols available to them.
! @5 q5 U9 [) z6 ^& [$ H* n3 XThe stem cell field is burgeoning, and, as I have seen within the ISSCR, there is a genuine- r" ?5 L: p! j. |( s4 A
push to share information and interact so that the field can move forward quickly. There* r$ ?8 s$ b) _. J' D2 z  r' v
is a drive to develop not only excellent basic research skills but to bring the findings+ m) L8 {6 R/ h
to clinical use so that patients can benefit. As a Hematology Attending Physician at
% J7 s* v5 V; rChildren’s HospitalBoston, I treat children who have pediatric blood diseases or leukemia  O8 h9 @! q" }
and am drawn by the need to translate our research findings into therapies to help treat a
+ R) R9 q: ~3 A$ Q* o# Qnumber of diseases. The promise is great, but we need to deliver, and I believe Current  X# r7 a/ r, e% m5 n8 c4 n8 L3 i
Protocols in Stem Cell Biology will help tremendously./ c; E$ V0 b7 R; ^' k
Leonard I. Zon- s* U: |; Q; I( y/ m5 j7 `7 k
Current Protocols in Stem Cell Biology
7 h. u  ^& k) M6 d: I( X$ u, rPublished online June 2007 in Wiley Interscience (www.interscience.wiley.com).
7 B; S9 z+ S; UDOI: 10.1002/9780470151808.scfores1
6 c% \+ c; q7 d0 [) y' v8 _Copyright C
2007 John
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/ Z. A0 }5 A$ \7 @4 N附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了
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xiaodongqin

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Jonathan

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horst

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